Relationship between gross motor function and magnetic resonance imaging findings in children with cerebral palsy

Authors

  • Sanjida Ahmed Department of Paediatric Neurology, IPNA, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh. https://orcid.org/0000-0002-4555-0642
  • Kanij Fatema Department of Pediatrics Neurology, IPNA, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.
  • Gopen Kumar Kundu Department of Pediatrics Neurology, IPNA, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.
  • Syeda Tabassum Alam Department of Pediatrics Neurology, IPNA, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.
  • Rebecca Sultana Department of Pediatrics Neurology, IPNA, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
  • Nahid Neela
  • Sadia Sultana Department of Pediatrics Neurology, IPNA, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.
  • Zannatul Ferdous Department of Pediatrics Neurology, IPNA, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.
  • Bikush Chandra Paul Department of Pediatrics Neurology, IPNA, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
  • Rumana Sultana Department of Obstetrics and Gynecology, Dhaka Medical College Hospital, Dhaka, Bangladesh.
  • Krishna Mohon Poddar Department of Pediatrics Neurology, National Institute of Neuro-Sciences and Hospital, Dhaka, Bangladesh
  • Shaheen Akhter Department of Pediatrics Neurology, IPNA, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/bsmmuj.v15i4.64152

Keywords:

Cerebral palsy, Gross Motor Function Classification System, Magnetic resonance imaging findings

Abstract

This cross-sectional study was carried out at the department of Pediatric Neurology, Institute of Pediatric Neurodisorder and Autism, Bangabandhu Sheikh Mujib Medical University, Dhaka with the aim to assess the relationship between gross motor function and MRI findings in children with cerebral palsy. The duration of the study was 12 months. All the cerebral palsy cases who met the selection criteria were enrolled. Detailed history taking and physical examination was done. The gross motor function of all cases was evaluated according to Gross Motor Function Classification System- Expanded and Revised (GMECS-E and R). Magnetic resonance imaging of brain was done in all enrolled patients and reports were evaluated. MRI findings were classified as maldevelopment, cortical and subcortical gray matter lesion, periventricular white matter injury, basal ganglia lesion, normal and other findings. A total of 45 children with cerebral palsy aged between 2 to 12 years were included in this study. Mean age of the children was 4.73 (+3.17) years. Male were 31 and female were 14 in number. Functionally majority patients were in GMFCS level IV (26.7%) and level V (20%). MRI findings were abnormal in 35 (77.78%) cases. Most common abnormal MRI finding was cortical and subcortical grey matter lesions 22 (48.9%). This study revealed that cortical and subcortical gray matter lesions were significantly associated with higher level of GMFCS (IV-V) (P=0.038) and maldevelopment of brain were also significantly associated with higher level of GMFCS (P=0.01). Normal MRI findings had significant association with mild to moderate GMFCS level (I-III) (P=0.012). From this study significant relationship was found between gross motor function and MRI of brain findings in children with cerebral palsy.

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Published

2023-02-05

How to Cite

Ahmed, S. ., Fatema, K. ., Kundu, G. K. ., Alam, S. T. ., Sultana, R., Neela, N. ., Sultana, S. ., Ferdous, Z. ., Paul, B. C. ., Sultana, R. ., Poddar, K. M. ., & Akhter, S. . (2023). Relationship between gross motor function and magnetic resonance imaging findings in children with cerebral palsy. Bangabandhu Sheikh Mujib Medical University Journal, 15(4), 8–15. https://doi.org/10.3329/bsmmuj.v15i4.64152

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