Bangabandhu Sheikh Mujib Medical University Journal https://www.banglajol.info/index.php/BSMMUJ <p>A quarterly, single-blinded peer-reviewed, open-access journal of Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh. Please submit your manuscript online. Each manuscript will be published immediately after acceptance.</p> <p>The journal follows the International Committee of Medical Journal Editors’ recommendations for the conduct, reporting, editing and publication of scholarly work in medical journals.</p> <p>The online version of the journal is available in HINARI, <a href="http://bit.ly/2qgfBS3">Directory of Open Access Journals</a>, Directory of Open Access Scholarly Resources, Journals for Free, WorldCat, Ingenta Connect, University of Toronto Libraries, University of New York Health Science Library, Wageningen University and Research, Genamics Journal Seek, SafetyLit, University of Saskatchewan, University of New South Wales Sydney Library, Princeton University Library. Research articles are available in ResearchGate.</p> en-US dgdabd@gmail.com (Mir Misbahuddin) banglajol.info@gmail.com (Md Fahmid Uddin Khondoker) Wed, 13 Mar 2019 05:23:05 +0000 OJS 3.1.1.4 http://blogs.law.harvard.edu/tech/rss 60 Detection of the recurrence of superficial urothelial carcinoma of urinary bladder by combined urine cytology and cystoscopy https://www.banglajol.info/index.php/BSMMUJ/article/view/38821 <p>The study was aimed to evaluate the accuracy of combined urine cytology and cystoscopy for the detection of the recurrence of superficial urothelial carcinoma of urinary bladder without bladder biopsy. A total 60 patients [males 48, females 12; age range 41-80 years (mean age- 63.15 years)] were included. Urine cytology as well as cystoscopy were done with a targeted biopsy taken from any apparently visible growth in the bladder. The systematic biopsy was taken where there was no growth. Reports of the cytology and cystoscopy were compared with the histopathology reports. It was found that 18 patients were cytology positive (false positive 2) and 42 patients were cytology negative (false negative 10) with sensitivity 61.5% and specificity 94%. During cystoscopy 24 patients were found recurrent growth in the bladder (false positive 3) and 36 patients were negative (false negative 5) with sensitivity 80.7% and specificity 91%. But when combined urine cytology and cystoscopic findings evaluated, the sensitivity and specificity were found 100% and 91% respectively. In conclusion, combined urine cytology and cystoscopy can be used for the detection of recurrence of superficial urothelial carcinoma of urinary bladder.</p> Mohammad Shafiqur Rahman, A. S. M. Azizur Rahman Siddique, Mohammad Saiful Islam, Saequa Habib, Faika Farah Ahmed ##submission.copyrightStatement## http://creativecommons.org/licenses/by/4.0 https://www.banglajol.info/index.php/BSMMUJ/article/view/38821 Wed, 13 Mar 2019 05:22:03 +0000 Effects of rehabilitation on the patients with chronic low back pain https://www.banglajol.info/index.php/BSMMUJ/article/view/37610 <p>This study was done to observe the effects of rehabilitation on chronic low back pain on 139 patient. They were divided into two groups:&nbsp; a) One group (n=71) received naproxen (non-steroidal anti-inflammatory drug, NSAID) with selective rehabilitation and b) another group (n= 68) treated with NSAID only. The patients were followed up weekly for eight weeks. The improvement was found in both groups after treatment. In patients with rehabilitation, the pre-treatment and post-treatment mean scores (Oswastry Disability Index, Visual Analogue Scale and Modified Zung Index) were 34.3 ± 9.8 and 9.9 ± 8.0 respectively (p&lt;0.001). Treatment with NSAID only reduced the mean scores from 34.9 ± 13.5 to 16.0 ± 14.4 (p&lt;0.001) after treatment. There was no significant difference in clinical improvement between the groups in pre-treatment compare with week one, rehabilitation group (29.7 ± 8.7) vs NSAID group (31.5 ± 13.8). While significant improvement was found in rehabilitation group in comparison to NSAID group after 8th week, rehabilitation group vs NSAID group scores were 10.0 ± 7.9 vs 15.9 ± 14.5 respectively (p= 0.004). In conclusion, rehabilitation can be used as an adjunct to NSAID for better improvement.</p> Md. Abdus Shakoor, M. Tariqul Islam, A. K. M. Salek, Md. Moyeenuzzaman ##submission.copyrightStatement## http://creativecommons.org/licenses/by/4.0 https://www.banglajol.info/index.php/BSMMUJ/article/view/37610 Wed, 13 Mar 2019 15:48:08 +0000 Effect of Momordica charantia on the removal of arsenic from different organs of arsenic-treated rat https://www.banglajol.info/index.php/BSMMUJ/article/view/40171 <p>The present study was designed to examine the effect of <em>Momordica charantia</em> ethanol extract on the removal of arsenic from different organs of the arsenic-loaded rat. The rats (n=30) were divided into 5 groups: a) control, b) arsenic-treated (200 µg/L), c) extract-treated (50 mg/day), and d) arsenic plus extract-treated (50 or 200 mg/kg). The rats were sacrificed on day 61. The study revealed that there were significant accumulation of arsenic in the liver, kidneys, intestine and skin. On the other hand, there was significant decrease in glutathione level in the liver. The administration of extract significantly decreased the amount of arsenic in all the organs tested and increased the glutathione level significantly in the liver. The maximum reduction of arsenic was found in skin (100%), liver (91.2%), intestine (89.2%) and kidney (83.1%). The maximum elevation of glutathione in liver was 48.3%.&nbsp; In conclusion, <em>M. charantia</em> reduces the arsenic level from different organs of the arsenic-loaded rat.</p> Shakila Akhter; Mir Misbahuddin ##submission.copyrightStatement## http://creativecommons.org/licenses/by/4.0 https://www.banglajol.info/index.php/BSMMUJ/article/view/40171 Thu, 14 Mar 2019 00:00:00 +0000 Off-pump versus on-pump coronary artery bypass grafting in patient of impaired renal function https://www.banglajol.info/index.php/BSMMUJ/article/view/40191 <p>The purpose of this study was to compare the renal function in patients undergoing coronary artery bypass grafting in off-pump and on-pump having pre-operative impaired renal function. In the on-pump, the serum creatinine and urea levels were significantly increased on post-operative day 1, 3 and 7. On day 1, it was maximum, then gradually decreased but not reached to pre-operative level. In case of off-pump, serum creatinine and urea levels were significantly increased on post-operative day 1 and 3. On day 1, it was maximum. Then decreased and the serum creatinine reached below pre-operative level on day 7. In case of on-pump, the creatinine clearance rate was significantly decreased on post-operative day 1, 3 and 7. On day 1, it was minimum. Then gradually increased but not reached the pre-operative level. In case off-pump, the creatinine clearance rate was significantly decreased on day 1 and 3. On day 1, it was minimum, then gradually increased and reached above the pre-operative level. A significant low level creatinine clearance rate was observed in on-pump group. Renal function was better preserved in patients undergoing off-pump in comparison to on-pump coronary artery bypass grafting.</p> Md. Alauddin, Aslam Hossain, Rezwanul Hoque, Asit Baran Adhikary ##submission.copyrightStatement## http://creativecommons.org/licenses/by/4.0 https://www.banglajol.info/index.php/BSMMUJ/article/view/40191 Thu, 14 Mar 2019 11:13:33 +0000 Glucose transporter 4 gene expression in peripheral blood leukocytes in type 2 diabetes mellitus https://www.banglajol.info/index.php/BSMMUJ/article/view/40467 <p>The purpose of this study was to examine the status of glucose transporter type-4 (GLUT4) gene expression in the peripheral blood leukocytes of type 2 diabetic patients and explore the correlation of GLUT4 expression with homeostasis model assessment-insulin resistance with a view to validate GLUT4 as a relatively less invasive alternate marker for insulin resistance. A total of 48 subjects were recruited. Among them, 23 subjects were diabetic and 25 were age, sex and body mass index-matched non-diabetic healthy control subjects. Insulin resistance, beta cell function and insulin sensitivity were assessed from the fasting blood samples. The mRNA levels of GLUT4 gene in the peripheral blood leukocytes were quantified by reverse transcriptase PCR. There was no significant alteration of GLUT4 gene status between type 2 diabetes mellitus and control. The GLUT4 gene expression showed a negative trend in the relationship with fasting glucose, HbA1c, insulin and insulin resistance in diabetic patients. In conclusion, the GLUT4 gene expression in the peripheral blood leukocytes cannot be used as a marker of insulin resistance.</p> Shahana Jasmin, Mohammad Ali, Mokerroma Ferdous, M. Iqbal Arslan, Subrata K. Biswas ##submission.copyrightStatement## http://creativecommons.org/licenses/by/4.0 https://www.banglajol.info/index.php/BSMMUJ/article/view/40467 Thu, 14 Mar 2019 13:19:27 +0000 Association between Helicobacter pylori infection and primary open-angle glaucoma https://www.banglajol.info/index.php/BSMMUJ/article/view/40484 <p>The pathological processes of primary open-angle glaucoma is unknown. Several studies show the relation between <em>Helicobacter pylori </em>infection and primary open-angle glaucoma. The purpose of this study was to assess the association between <em>H. pylori </em>infection and primary open-angle glaucoma. Forty patients of diagnosed primary open-angle glaucoma were selected as case and 40 participants without primary open-angle glaucoma were selected as control as per inclusion and exclusion criteria. Complete clinical evaluation including history, physical examination, relevant ocular examinations and laboratory investigations were performed. Serologic evidence of <em>H. pylori </em>infection was found in 75% of patients with primary open-angle glaucoma and 30% of patients without primary open-angle glaucoma which achieved statistically significant difference (p=0.000, OR=7.00 and CI 95% =2.61-18.74). <sup>13</sup>C urea breath test was positive in 70% in case group and 37.5% in control group which also achieved statistically significant difference&nbsp; (p=0.003, OR=3.89 and CI 95% =1.53-9.87). The findings revealed significant association between <em>H. pylori </em>infection and primary open-angle glaucoma.</p> <p>&nbsp;</p> Sayaka Sultana, Nazneen Khan, Chonchol Kumar Ghosh, Ahmed Abu Saleh, Md. Shafiqul Islam ##submission.copyrightStatement## http://creativecommons.org/licenses/by/4.0 https://www.banglajol.info/index.php/BSMMUJ/article/view/40484 Thu, 14 Mar 2019 13:58:53 +0000 Off pump coronary artery bypass grafting in awake patient https://www.banglajol.info/index.php/BSMMUJ/article/view/39368 <p>This article has no abstract. The first 100 words appear below:</p> <p>A 60-year-old male patient was admitted into the department as a diagnosed case of ischemic heart disease and his coronary angiogram reveals triple vessel disease (80-90% lesion in the mid part of left anterior descending artery; 90% lesion in the distal part of obtuse marginal and 99% stenosis in the distal part of right coronary artery). The patient was suffering from chest pain for last 3 months which aggravated by exertion and radiates along the neck and left arm.&nbsp;The patient was non-diabetic and non-hypertensive.</p> Md. Sazzed -Al- Hossain, Kamrun Nahar, Golam Mursalin, Redoy Ranjan, Sanjoy Kumar Saha, Asit Baran Adhikary ##submission.copyrightStatement## http://creativecommons.org/licenses/by/4.0 https://www.banglajol.info/index.php/BSMMUJ/article/view/39368 Fri, 15 Mar 2019 00:57:02 +0000 A 10-year-old boy presented with recurrent episodes of diarrhea, low grade, irregular fever and severe wasting https://www.banglajol.info/index.php/BSMMUJ/article/view/39928 <p>This article has no abstract. The first 100 words appear below:</p> <p>A 10-year old boy, the only issue of his deceased parents, was admitted to the department for the management of recurrent episodes of diarrhea and severe wasting for 2.5 months, low grade, irregular fever with evening rise of temperature, anorexia and repeated attack of skin blister for the last 1 year. The patient complained of chronic, painless, non-bloody, profuse watery diarrhea with a weight loss of 10 kg (decrease to 18 kg from 28 kg prior to illness).&nbsp;He also complained of cough for the last seven days. His father was a driver and died at his 1 year of age due to an unknown disease.</p> Hazera Akter, Md. Wahiduzzaman Mazumder, A. S. M. Bazlul Karim, Subarna Rani Das, Saidul Islam Sumon ##submission.copyrightStatement## http://creativecommons.org/licenses/by/4.0 https://www.banglajol.info/index.php/BSMMUJ/article/view/39928 Fri, 15 Mar 2019 02:01:46 +0000 A 22-year-old male with pain and tooth surface loss on multiple teeth https://www.banglajol.info/index.php/BSMMUJ/article/view/40165 <p>This article has no abstract. The first 100 words appear below:</p> <p>A 22-year-old male reported to the outpatient department with the complaints of occasional pain and tingling sensation on his maxillary left posterior teeth and mandibular anterior teeth for 3 to 4 months with slight mobility of mandibular anterior teeth. He had no significant medical history as well as no history of trauma and familial history of similar disease.&nbsp;He also stated that he went to Dhaka Dental College where he received clinical and radiological investigations and diagnosed as a case of external tooth resorption. In the Dhaka Dental College, upper left&nbsp; 1<sup>st</sup> and 2<sup>nd</sup> premolar, mandibular right central and lateral incisor teeth were extracted.</p> Sageer Ahmed, Shegufta Tabassum, Mozammal Hossain, Md. Mujibur Rahman Howlader, Md. Joynal Abdin, Md. Shamsul Alam ##submission.copyrightStatement## http://creativecommons.org/licenses/by/4.0 https://www.banglajol.info/index.php/BSMMUJ/article/view/40165 Fri, 15 Mar 2019 03:04:39 +0000 A 16-year-old boy with chronic discharging sinus on upper left lateral incisor tooth https://www.banglajol.info/index.php/BSMMUJ/article/view/40170 <p>This article has no abstract. The first 100 words appear below:</p> <p>A 16-year-old boy referred to our department with chronic discharging sinus during the course of root canal treatment on the upper left lateral incisor tooth from a private dental clinic. The patient had a history of trauma to the tooth 1 year back. On clinical examination, the coronal portion of the upper left lateral incisor tooth was found to have filled with temporary restorative material. The tooth was sensitive to palpation and percussion with the presence of a sinus tract.&nbsp;On vitality test, there was no response to heat and cold test.</p> Ridwana Kawsar, Mozammal Hossain, Md. Mujibur Rahman Howlader, Mir Md. Mofazzal Hossain, Md. Joynal Abdin, Md. Shamsul Alam ##submission.copyrightStatement## http://creativecommons.org/licenses/by/4.0 https://www.banglajol.info/index.php/BSMMUJ/article/view/40170 Fri, 15 Mar 2019 04:58:19 +0000 A 48–year–old female presented with severe neck pain https://www.banglajol.info/index.php/BSMMUJ/article/view/40522 <p>This article has no abstract. The first 100 words appear below:</p> <p>A 48-year-old married female got admitted on 8<sup>th</sup> September 2017 into the Boarder Guard Hospital, Pilkhana, Dhaka, Bangladesh with the complaints of severe neck pain associated with low grade backache for the last four years. This patient is hailing from Soliabazar, Jashore, Southwestern region of Bangladesh where she was treated with local doctors by cervical collar and analgesics for her neck and back pain.&nbsp;As the pain did not subside, so she was brought by her brother-in-law who is a BGB soldier to Boarder Guard hospital for better management.</p> Mohammad Mizanur Rahman, Susane Giti, Md. Monirul Islam, Mohammad Shahidul Islam, Mreenal Kanti Sarkar, Abdullah Al Maruf, Morshed Rashid ##submission.copyrightStatement## http://creativecommons.org/licenses/by/4.0 https://www.banglajol.info/index.php/BSMMUJ/article/view/40522 Fri, 15 Mar 2019 05:55:25 +0000 A 2-year-old male child with diffuse abdominal pain, mass in the abdomen and red currant jelly stool https://www.banglajol.info/index.php/BSMMUJ/article/view/40453 <p>This article has no abstract. The first 100 words appear below:</p> <p>A 2-year-old male child, the second issue of non-consanguineous parents, from average socio-economic status hailing from Dinajpur, Bangladesh was attended at Pediatric Surgery outpatient department with the complaints of vague diffuse abdominal pain in the lower right side of abdomen and around the umbilical region for last 3 days. His mother also reported the feeling of a solid mass in the abdomen during dressing of her child.&nbsp;Then, gradually his problems were increasing in nature with several times of nausea, vomiting, and the passage of blood mixed stool three times before his admission.</p> Md. Golam Hafiz, Chowdhury Yakub Jamal, Md. Anwarul Karim, Afiqul Islam, Md. Iqbal Hossain, A. K. M. Nurul Kabir, Md. Tosaddeque Hossain Siddiqui ##submission.copyrightStatement## http://creativecommons.org/licenses/by/4.0 https://www.banglajol.info/index.php/BSMMUJ/article/view/40453 Fri, 15 Mar 2019 00:00:00 +0000