Bangabandhu Sheikh Mujib Medical University Journal

Uncommon CD markers in acute myeloid leukemia

2019-01-16T12:58:04+00:00

This study was done to assess the unusual CD expression in 100 cases of acute myeloid leukemia from October 2016 to April 2018. The age limit was from 3 to 50 years. Four color flow cytometry was used to diagnose the fresh aspirated bone marrow or peripheral blood sample of acute leukemia. The unusual lymphoid CD expression on myeloblasts was analyzed. Among the cases, 44% were acute myeloid leukemia, 52% of patients were of acute lymphoblastic leukemia and mixed phenotype acute leukemia was 4%. Aberrant CD expression was observed in 58% acute myeloid leukemia patients. Both aberrant CD5 and CD7 lymphoid markers expressed in acute myeloid leukemia patients were 4.2%. Aberrant CD7, CD5, cCD79a and cCD3 were in 45.8%, 33.3%, 8.3%, 8.3% of acute myeloid leukemia patients respectively. In acute myeloid leukemia, the frequency of aberrant CD expression was compared with recent international data.

Prognosis of ischemic stroke patients with or without collateralization after carotid stenosis

2019-01-16T12:58:04+00:00

The objective of this study was to see the association of the prognosis of ischemic stroke patients with or without collateralization after carotid stenosis. This study was conducted on 36 patients presenting with acute ischemic stroke who were going through digital subtraction angiography from March 2017 to March 2018. Collateralization status after unilateral or bilateral stenosis was evaluated. Modified ranking scale (mRS) score was measured on the first day of the stroke and after three months. The disability of ischemic stroke patients was compared between patients who developed collateralization and who had not. Among them, 61.6% developed collateralization. Among the patients who developed collateralization after three months, 90.9% patients had mRS scale of ≤2 and who not developed collateralization, 85.7% patients had mRS scale of ≤2. In both the groups, the p value was <0.05. It can be concluded that carotid stenosed patients who suffered from ischemic stroke, most of the patients disability improved to some extents whether collateralization developed or not among the major vessels.

Frequency and nature of pain following single visit root canal treatment

2019-01-16T12:58:08+00:00

The purpose of this study was to compare the frequency and nature of pain between the vital inflamed (n=55) and non-vital (n=55) teeth that received single visit root canal treatment. The frequency and nature of pain were assessed as no pain, mild, moderate and severe pain on day 2 and day 7. The results showed that 76.4 and 85.5% participants felt no pain in vital inflamed teeth on day 2 and day 7, respectively. On the other hand, 63.6 and 74.5% participants felt no pain in non-vital teeth on day 2 and day 7, respectively. The remaining participants only felt mild to moderate pain. There were no significant difference between the two groups (p=0.435 on day 2 and p=0.371 on day 7). The results suggested that single visit root canal treatment is equally effective in both vital inflamed and non-vital teeth.

A comparative clinical study on efficacy of nanofilled resin-modified and conventional glass ionomer pit and fissure sealant in molar tooth

2019-01-16T12:58:07+00:00

The present study compared the clinical performance of nanoparticulated resin modified glass ionomer and conventional glass ionomer pit and fissure sealant on permanent molars. Fifty patient having bilateral occlusal grooves in pits and fissures of the occlusal surface were included for this study where 50 teeth were treated with nanopaticulated resin modified and the remaining 50 teeth were subjected to conventional glass ionomer sealants. The color match, retention and marginal adaptation were assessed at 3, 6 and 12 months and statistical analysis was performed by Chi-square test to assess the difference between the two sealants; a values of <0.05 was considered as statistically significant. The results showed that although there were no significant differences between two sealants at baseline and 3 months observation period but nanoparticulated resin modified glass ionomer sealants showed better clinical performance than that of conventional glass ionomer sealants at 12 months and the differences between two sealants were statistically significant (p<0.05). It can be concluded that naqnoparticulated resin modified glass ionomer sealant exhibited better color stability, more retention, and better marginal adaptation than those of conventional glass ionomer sealants at 12 months observation period.

Coccygectomy can be a option for coccydynia which is refractory to medical treatment

2019-01-16T12:58:03+00:00

The aim of this study was to evaluate the clinical outcome of coccygectomy those who were refractory to conservative treatment. Twenty patients (5 males, 15 females) underwent total coccygectomy when coccygodynia did not responding to medical treatment July 2013 to September 2018. All the patients timely attended with non-traumatic (n = 12) and traumatic (n = 8) cause with mean follow-up visits of 24 months (range 18-28 months). The outcome pain intensity was evaluated by visual analogue scale (VAS) in sitting position and during daily activities. Three patients had infection which improved after antibiotic therapy. The VAS improved from 6.4 ± 0.9 to 2.1 ± 0.9 for sitting and from 5.8 ± 0.9 to 1.6 ± 0.6 for daily activities. Improvement in pain and daily activities were significant at the final follow-up. Ninety percent patients were satisfied with the operation.

Effect of mean ocular perfusion pressure on primary open angle glaucoma

2019-01-16T12:58:03+00:00

Primary open angle glaucoma is the most common form of glaucoma and it remains asymptomatic until the late stage of the disease. The purpose of this study is to compare the mean ocular perfusion pressure with the primary open angle glaucoma. A total of 60 study subjects were divided into two following groups: a) newly diagnosed patients with primary open angle glaucoma (case) and b) age and sex-matched healthy volunteers (control). The intraocular pressure and blood pressure were measured 3 hourly from 8:00 am to 11:00 pm. The mean ocular perfusion pressure of the right eyes in untreated primary open angle glaucoma was 39.9 ± 7.5 mm Hg whereas it was 47.7 ± 7.7 mm Hg in the control. The odds ratio was 6.6 (95% CI, 2.1-20.5; p=0.002). The right eyes of untreated primary open angle glaucoma had 6.6 times more risk compared to the control group. The mean ocular perfusion pressure of left eyes in untreated primary open angle glaucoma was 39.9 ± 7.5 mm Hg and 48.6 ± 4.0 mm Hg in the control group. The odds ratio was 5.7 (95% CI, 1.8-17.5; p=0.004). The left eyes of untreated primary open angle glaucoma had 5.7 times more risk compared to control group. The findings revealed the evidence of vascular mechanism in glaucoma pathogenesis: Reduction of mean ocular perfusion pressure ≤48 mm Hg, may lead to daily repetitive ischemic insult to the optic nerve.

Hematological changes associated with hepatitis by hepatitis E virus

2019-01-16T12:58:02+00:00

The purpose of the study was to find out the changes in the common hematological parameters in patients (n=998) of acute viral hepatitis caused by hepatitis E virus from April to May, 2018. The mean hemoglobin level was 13.5 g/dL. However, seven patients were found to have hemoglobin level <11.0 g/dL. The mean red cell count was 4.5 x 10¹²/L. The mean packed cell volume was 40.6%. The mean white blood cell count was 7.1 x 10⁹/L. However, leucopenia was found in 8 cases. The mean platelet count was 186.2 x 10⁹/L. Among the hematological changes associated with hepatitis E virus infection, thrombocytopenia is a notable finding.

Comparative efficacy of mineral trioxide aggregate and biodentine for the repair of pulpal floor perforation

2019-01-16T12:58:08+00:00

In the present study, the clinical outcome of mineral trioxide aggregate and Biodentine as repairing materials in the management of pulpal floor perforation was compared in vivo. Thirty teeth having pulpal floor perforation were enrolled in this study, out of which 15 perforations were repaired with mineral trioxide aggregate and the remaining 15 were subjected to Biodentine treatment. Following perforation repair, each tooth was then subjected to root canal therapy. Patients were recalled at 3, 6 and 12 month interval. The assessment of pain, pain on palpation, tenderness on percussion, and radiological evaluation was performed to determine the repair ability of pulpal floor perforation. Statistical analysis was performed with Chi-square test between the two groups and a value of p<0.05 was considered as statistically significant. The results showed that pain, tenderness on percussion as well as the thickness of periodontal ligament was gradually decreased and the communication between the perforation and oral cavity was successfully repaired following MTA and Biodentine therapy. Furthermore, the differences between MTA and Biodentine were not statistically significant. It can be concluded that clinical outcome and repair of pulpal floor perforation by Biodentine is almost similar to MTA.

A 9-year-old girl presented with jaundice, abdominal distension, hematemesis, melena and pleural effusion

2019-01-16T12:58:06+00:00

This article has no abstract. The first 100 words appear below:

A 9-year-old girl of non-consanguineous parents presented at the outpatient department with the history of jaundice and abdominal distension for 20 days and respiratory distress for 7 days. She also complained of bloody vomiting without any melena. The mother gave the history of abdominal pain for 2 days which was diffuse in nature. Her menarche had not started yet. Her younger sister is healthy. She had no history of fever, constipation, family history of liver disease, sib death, contact with known tuberculosis patient, blood transfusion or parenteral medication. On examination, she was afebrile, moderately pale, dyspnea and leukonychia. Bilateral pedal edema was present.

A 17-month-old girl presented with jaundice, hepatosplenomegaly, ascites and scaly erythematous skin lesion

2019-01-16T12:58:05+00:00

This article has no abstract. The first 100 words appear below:

A 17-month-old girl, only issue of non-consanguineous parents, hailing from Sirajgonj, Bangladesh immunized as per EPI schedule got admitted to the inpatient department with the history of abdominal distension, jaundice, not growing well along with scaly skin lesion over scalp, chest, palm and sole for 9 months. She was reasonably well 9 months back. Then she developed abdominal distention which was increasing day-by-day associated with gradually deepening jaundice. There was also a history of irregular fever and cough for 1 month. Fever was high-grade irregular in nature, subsided by taking antipyretics in conjunction with non-productive cough. There was no history of contact with the tuberculosis patient, any surgery or dental procedure, family history of liver disease, but the history of one unit blood transfusion.

A 12-year-old boy presented with fever and left-sided upper abdominal pain

2019-01-16T12:58:06+00:00

This article has no abstract. The first 100 words appear below:

A 12-year-old boy of non-consanguineous parents presented with the history of fever and left sided upper abdominal pain for 1 month. His fever was high grade, intermittent, associated with chills and rigor. The abdominal pain was dull aching in nature without any radiation, aggravating or relieving factors. His bowel habit was normal. The child had no history of jaundice, cough, respiratory distress, burning sensation during micturition, earache, skin infection, contact with tubercular patient, blood transfusion or parenteral medica-tion. On examination, she was fretful, febrile, mode-rately pale, and anicteric. Tachycardia was present. Per abdominal examination revealed tenderness at the left hypochondriac region.

Activities of institutional quality assurance cell of Bangabandhu Sheikh Mujib Medical University

2019-01-16T12:58:09+00:00

No abstract