Bangabandhu Sheikh Mujib Medical University Journal 2020-01-28T13:11:57+00:00 Mir Misbahuddin Open Journal Systems <p>A quarterly, single-blinded peer-reviewed, open-access journal of Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh. Please submit your manuscript online. Each manuscript will be published immediately after acceptance.</p> <p>The journal follows the International Committee of Medical Journal Editors’ recommendations for the conduct, reporting, editing and publication of scholarly work in medical journals.</p> <p>The online version of the journal is available in HINARI, <a href="">Directory of Open Access Journals</a>, Directory of Open Access Scholarly Resources, Journals for Free, WorldCat, Ingenta Connect, University of Toronto Libraries, University of New York Health Science Library, Wageningen University and Research, Genamics Journal Seek, SafetyLit, University of Saskatchewan, University of New South Wales Sydney Library, Princeton University Library. Research articles are available in ResearchGate.</p> Immunohistochemical expression of BerEP4, CK7 and EMA in basal cell carcinoma of the skin 2020-01-28T13:11:57+00:00 Vladimír Bartoš <p>The aim of this study was to evaluate the immunohistochemical expression status of BerEP4, EMA and CK7 in cutaneous basal cell carcinoma (BCC) and to find out whether there is some difference in the expression pattern related to the anatomic location of lesions. Biopsy specimens from 32 cases of BCC of the skin were enrolled. All samples were immunohistochemically stained for EpCAM (clone BerEP4), EMA (clone E29), and CK7 (clone OV-TL 12/30). All cases (32/32; 100%) were strongly positive for BerEP4, while the vast majority of tumors (28/32) were completely negative for EMA. Four BCCs (12.5%) exhibited a focal staining for EMA, but it was only sporadic and did not exceed 5% of tumor epithelium. Cytoplasmic expression of CK7 was found in 19 cases (19/32; 59.4%). Comparing both, the chronically sun-exposed and the intermittently sun-exposed anatomic locations, the percentages of CK7-positive BCCs were 47.8 and 88.9%, respectively. In conclusion, all lesions showed a strong expression of BerEP4, the use of this marker is helpful especially in individuals suspected of having multifocal BCC with many microlesions, morpheic BCC, or BCCs with mixed histomorphology.</p> 2019-12-22T23:51:46+00:00 ##submission.copyrightStatement## Dhaka stress scale-adolescent: A scale for assessing psychosocial stressors among adolescents 2020-01-28T13:11:56+00:00 Mohammad S. I. Mullick Sultana Algin Monirul Islam Adrian Phillipson Jhunu S. Nahar Nahid Mahjabin Morshed Hafizur Rahman Chowdhury Selina Fatema Binte Shahid <p>This study was aimed to produce a culturally validated scale to determine the presence of stressful life events among adolescents in Bangladesh, and formulate the relative life change units for each event. The study used qualitative research, including a focus group and questionnaire, and quantitative analysis in the validation process. Researchers first developed a provisional stress scale that was translated in Bangla through a translation exercise. Using an open-ended question along with this provisional scale on a school sample of 449 (228 rated on imagination and 221 on actual experience) adolescents, researchers developed Dhaka stress scale– adolescent with 56 items and predictive interpretation of the overall score was made. Content validity was found excellent as item level content validity index was around 1 and the scale level validity index was 0.93. The correlation coefficient was 0.72 between this scale and adolescent life events stress scale. For reliability, Cronbach’s alpha values were ranged from 0.83 to 0.97. The scale is simple to administer to assess stress in adolescents and usable in both clinical and research settings.</p> 2019-12-23T00:36:48+00:00 ##submission.copyrightStatement## Intralesional steroid and ultrasound therapy in patients with carpal tunnel syndrome 2020-01-28T13:11:55+00:00 Md. Israt Hasan Syed Mozaffar Ahmed <p>The study aimed to compare the effects of intralesional steroid injection and ultrasound therapy for the treatment of carpal tunnel syndrome. A total 130 patients divided into 2 groups: a) One group (n=65) received intralesional corticosteroid injection along with wrist splint, exercise, naproxen sodium 500 mg tablet and omeprazole 20 mg capsule twice daily for 2 weeks; b) Another group received (n=65) ultrasound therapy (10 min/day, 3 days/week for 4 weeks) along with&nbsp; Wrist splint for 4 weeks, exercises for 4 weeks, naproxen sodium 500 mg tablet and omeprazole 20 mg capsule twice daily for 2 weeks. The patients were followed-up 2 weekly for 4 weeks. The visual analogue score, symptom severity scores and functional status scores were significantly improved within each group at week 2 (p&lt;0.05) and week 4 (p&lt;0.05) except for the symptom severity score at (p&gt;0.05). The improvement in symptom severity scores and functional status scores in the intralesional steroid group was more than in the ultrasound therapy group after 4 weeks.</p> 2019-12-23T03:30:59+00:00 ##submission.copyrightStatement## Induction of reparative dentin by calcium silicate-based material as direct pulp capping agent 2020-01-28T13:11:54+00:00 Mozammal Hossain Mahmood Sajedeen Yukio Nakamura <p>This study was performed to examine whether calcium silicate could induce reparative dentin formation without eliciting any adverse effect in direct pulp capping of premolar teeth. Twenty participants who need extraction of their 4 healthy permanent premolar teeth for orthodontic reasons were included in this study. Following the surgical procedure, the exposed pulp tissue was treated either with calcium silicate or covered with calcium hydroxide paste. On day 3, 7, 14 and 28, the experimental teeth was extracted and examined using light microscopy and histometric analysis to observe the inflammatory changes and the amount of reparative dentin formation. The results showed that in the&nbsp;calcium silicate treated teeth, substantial amounts of dentine-like tissue was formed on day 14 and mostly located on the exposure site. It was also observed in the calcium hydroxide treated teeth but dentin-like tissue located at a distance from the exposure site. The total amount of reparative dentine formed in the&nbsp;calcium silicate-treated teeth was significantly higher (p&lt;0.005) than in the calcium hydroxide-treated specimens. In conclusion that the calcium silicate indices pulpal wound healing and reparative formation in the exposed teeth without affecting the normal function of the remaining pulp.</p> 2019-12-23T04:49:25+00:00 ##submission.copyrightStatement## A 50-year-old female, diabetic patient with chest pain and dizziness 2020-01-28T13:11:53+00:00 Redoy Ranjan Dharmendra Joshi Mohammad Ata Ullah Prashant Bajracharya Sanjoy Saha Asit Baran Adhikary <p>This article has no abstract. The first 100 words appear below:</p> <p>A 50-year-old female got admitted on June 18, 2019 with&nbsp; complaints of central chest pain for three years and dizziness for the last two months. The chest pain was compressive in nature, moderate to severe in intensity and radiating to the medial side of the left upper limb and neck. It used to get aggravated during exertion and initially relieved by taking rest but later she had to take medicine to relieve the chest pain. The pain was not associated with meal, palpitation, dyspnoea, cough or fever. She also complained of dizziness and easy fatigability while walking for the last two months.</p> 2019-12-23T15:22:18+00:00 ##submission.copyrightStatement## A 10-year-old girl presenting with jaundice, deterioration of school performance and itching 2020-01-28T13:11:52+00:00 Md. Benzamin Zannatul Ferdous Sonia Md. Rukunuzzaman Khan Lamia Nahid Bishnu Pada Dey <p>This article has no abstract. The first 100 words appear below:</p> <p>A 10-year-old immunized girl, 6<sup>th</sup> issue of consanguineous parents, presented with the complaints of jaundice for the last 2 years and deterioration of school performance for the same duration. She also had generalized itching for the last 6 months. She had no history of altered sleep pattern, any gastrointestinal bleeding, surgical or dental procedures, history of blood and blood products transfusion, taking any offending drugs, sib death or family history of such type of illness.</p> 2019-12-24T01:18:45+00:00 ##submission.copyrightStatement## A 15-year-old boy with huge facial swelling, recurrent severe epistaxis, progressive proptosis, nasal obstruction and impaired hearing on right side 2020-01-28T13:11:51+00:00 Md. Asaduzzaman Shamsul Alam Md. Wares Uddin K. M. Tarikul Islam Mahmudul Hasan <p>This article has no abstract. The first 100 words appear below:</p> <p>A 15-year-old male hailing from Khagrachhari was admitted into the department with the complaints of swelling on the right side of face for 10 months with recurrent severe epistaxis, progressive proptosis, unilateral nasal obstruction and impairment of hearing for two months. On extraoral examination, there was a firm non-tender, nonmobile, fixed swelling on the right side of cheek causing facial asymmetry measuring about 10 × 12 cm in size extending from upper eyelid to middle of the right cheek supero-inferiorly and pre-auricular area to the medial wall of nose postero-anteriorly</p> 2019-12-24T14:52:20+00:00 ##submission.copyrightStatement## A 14-year-old boy presenting with gradual abdominal distension and occasional abdominal pain for 2 years 2020-01-28T13:11:50+00:00 Nazmul Hassan Mahmudul Hasan Kaniz Fathema Khondaker Mobasher Fahmida Begum Wahiduzzaman Mazumder <p>This article has no abstract. The first 100 words appear below:</p> <p>A 14-year-old boy, 4<sup>th</sup> issue of his non-consanguineous parents got admitted in the Department with the complaints of gradual abdominal distension and occasional abdominal pain since two years of his age. There was no history of jaundice, upper gastrointestinal bleeding, fever, contact with a known case of tuberculosis patient or family history of such type of illness. On examination, he was alert, anicteric, no facial dysmorphism, vitally stable, no stigmata of chronic liver disease and anthropometrically well thrived.</p> 2019-12-25T03:07:21+00:00 ##submission.copyrightStatement## A 42-year-old female presented with asymptomatic massive splenomegaly 2020-01-28T13:11:49+00:00 Abed Hussain khan Esrat Khan Lubna Mohammad Ferdous Ur Rahaman Mahbubur Rahman Farzana Rahman Naila Atik Khan <p>This article has no abstract. The first 100 words appear below:</p> <p>A 42-year-old female hailing from Brahmanbaria, Bangladesh was admitted with the complaints of abdominal pain which was more marked in the left upper abdomen. Fifteen days before admission in this department, she had a history of physical assault, since then she was experiencing pain over different parts of her body including abdomen. She took analgesic for this pain. Other regional pain subsided but the abdominal pain was persisting.</p> 2019-12-26T11:49:56+00:00 ##submission.copyrightStatement##