A 43-year-old man with recurrent spontaneous hypoglycemia
Keywords:
Insulin autoimmune syndrome, Hypoglycemia, Insulin antibodyAbstract
Insulin autoimmune syndrome (IAS) is a rare hypoglycemic disorder characterized by recurrent episodes of fasting or late post-prandial hypoglycemia with a very high level of insulin and positive insulin antibody. We are reporting a case of recurrent episodes of spontaneous hypoglycemia in a 43-year-old male with biopsy-proven autoimmune hepatitis. After a thorough evaluation, he was found to have endogenous hyperinsulinemia. As there was no apparent cause of endogenous hyperinsulinemia, he was evaluated for insulin antibody which was found to be raised. A diagnosis of IAS was made, and he was put on a small frequent meal with tab diazoxide, and he improved. Although it is an uncommon disease, it should be kept in the differential diagnosis of spontaneous hypoglycemia.
J Assoc Clin Endocrinol Diabetol Bangladesh, July 2024;3(2): 71-74
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Copyright (c) 2024 Md Hasanul Islam, Md Ashiqur Rahman, Murshed Ahamed Khan, Samira Mahjabeen, Marufa Mustari, Md Fariduddin
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