Role of environmental and genetic factors in autism spectrum disorder

  • Zakia Sultana Biotechnology and Genetic Engineering Discipline, Khulna University, Khulna 9208
  • Sarder Nasir Uddin Biotechnology and Genetic Engineering Discipline, Khulna University, Khulna 9208
  • Asif Ahmed Biotechnology and Genetic Engineering Discipline, Khulna University, Khulna 9208
Keywords: ASD, Environmental, Genetic

Abstract

The aim of this study was to find out the environmental as well as genetic factors responsible for increasing the number of autism spectrum disorder (ASD) patients in Bangladesh. A questionnaire was developed based on 12 environmental factors and genetic aspects. Sixty six patients of ASD and 66 non-ASD control were selected randomly. Among the environmental factors, the age of the mother, premature birth, air pollution, age of the father, hypoxia during childbirth and oral contraceptive came out as significant (p<0.05) factors for ASD incidence compared to the control. Association of multiple factors on an individual was found to be crucial to enhance the risk and exposure to five and six factors was statistically significant (p<0.05) for ASD development. Prospective parents should try to keep the number of risk factors as low as possible before 1-2 months of pregnancy, during pregnancy and 1-2 years after the child birth (for child only).

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Author Biographies

Zakia Sultana, Biotechnology and Genetic Engineering Discipline, Khulna University, Khulna 9208

MS student

Sarder Nasir Uddin, Biotechnology and Genetic Engineering Discipline, Khulna University, Khulna 9208

Professor

Asif Ahmed, Biotechnology and Genetic Engineering Discipline, Khulna University, Khulna 9208

Associate Professor

Published
2017-05-22
How to Cite
Sultana, Z., Uddin, S., & Ahmed, A. (2017). Role of environmental and genetic factors in autism spectrum disorder. Bangabandhu Sheikh Mujib Medical University Journal, 10(2), 76-83. https://doi.org/10.3329/bsmmuj.v10i2.32385
Section
Original Articles