Atypical presentation of sickle cell disease

Authors

  • Md. Abdul Aziz Department of Hematology, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka
  • Surozit Kumar Sarkar Department of Hematology, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka
  • Farzana Rahman Department of Hematology, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka
  • Showrab Biswas Department of Hematology, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka
  • Saqi Md. Abdul Baqi Department of Hematology, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka
  • Masuda Begum Department of Hematology, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka

DOI:

https://doi.org/10.3329/bsmmuj.v10i1.31032

Keywords:

Anemia, Sickle cell disease

Abstract

A 20 year old female presented with a history of frequent syncopal attack since her childhood. Each episode persisted 5-10 min without having any aggravating factor or prodrome. She had persistent generalized bodyache aggravating during the winter. She had jaundice and episodic abdominal pain. She received 1 unit of blood transfusion 4 months back and improved sympto-matically. Patient was mildly anemic, moderately icteric and had mild splenomegaly. Over these long periods of her illness she was thoroughly evaluated several times. Her biochemical and neurological evaluation revealed no abnormalities. But she was treated with anticonvulsant for long time empirically without significant improvement. Her CBC showed microcytic hypochromic anemia. She was negative for Wilsons disease. Reticulocyte count was high. Coombs test was negative. Osmotic fragility test was positive. Hemoglobin electrophoresis revealed Hb-S 60%. Sickling test was found positive. Finally it was diagnosed as a case of HbS/?+.

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Author Biography

Masuda Begum, Department of Hematology, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka

Professor

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Published

2017-02-24

How to Cite

Aziz, M. A., Sarkar, S. K., Rahman, F., Biswas, S., Baqi, S. M. A., & Begum, M. (2017). Atypical presentation of sickle cell disease. Bangabandhu Sheikh Mujib Medical University Journal, 10(1), 27–28. https://doi.org/10.3329/bsmmuj.v10i1.31032

Issue

Section

Case Reports