Uncommon CD markers in acute myeloid leukemia

  • Azad Abul Kalam Department of Hematology, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka, Bangladesh
  • Md. Rafiquzzaman Khan Department of Hematology, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka, Bangladesh
  • A. B. M. Hassan Habib Department of Hematology, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka, Bangladesh
  • Masuda Begum Department of Hematology, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka, Bangladesh
Keywords: Blood cancer, CD marker, Myeloid leukemia

Abstract

This study was done to assess the unusual CD expression in 100 cases of acute myeloid leukemia from October 2016 to April 2018. The age limit was from 3 to 50 years. Four color flow cytometry was used to diagnose the fresh aspirated bone marrow or peripheral blood sample of acute leukemia. The unusual lymphoid CD expression on myeloblasts was analyzed. Among the cases, 44% were acute myeloid leukemia, 52% of patients were of acute lymphoblastic leukemia and mixed phenotype acute leukemia was 4%. Aberrant CD expression was observed in 58% acute myeloid leukemia patients. Both aberrant CD5 and CD7 lymphoid markers expressed in acute myeloid leukemia patients were 4.2%. Aberrant CD7, CD5, cCD79a and cCD3 were in 45.8%, 33.3%, 8.3%, 8.3% of acute myeloid leukemia patients respectively. In acute myeloid leukemia, the frequency of aberrant CD expression was compared with recent international data.

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Published
2018-12-25
How to Cite
Kalam, A., Khan, M., Habib, A. B. M., & Begum, M. (2018). Uncommon CD markers in acute myeloid leukemia. Bangabandhu Sheikh Mujib Medical University Journal, 11(4), 267-269. https://doi.org/10.3329/bsmmuj.v11i4.37281
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Original Articles