Miller Fisher Variant of Guillain-Barré Syndrome: A Case Report & Clinical Review

  • Partha Pratim Das Assistant Professor, Department of Medicine, Dhaka Medical College, Dhaka
  • Sarmistha Biswash Assistant Professor, Department of Medicine, Dhaka Medical College, Dhaka
  • Md. Enamul Karim Professor, Department of Medicine, Dhaka Medical College, Dhaka
  • Nigar Sultana Ahmed Assistant Registrar, Department of Medicine, Dhaka Medical College, Dhaka
  • Badrul Islam PHD Student, Erasmus MC, Dhaka
  • Shekhar Kumar Mandal Medical Officer, Department of Medicine, Dhaka Medical College, Dhaka
  • Abu Hena Md. Raihanuzzaman Sarkar Medical Officer, Department of Medicine, Dhaka Medical College, Dhaka
Keywords: Abnormal reflex, areflexia, ataxia, Guillain-Barré syndrome, ophthalmoplegia, Nerve Conduction Velocity (NCV)

Abstract

Miller Fisher syndrome (MFS) is an uncommon variant of Guillain-Barré syndrome (GBS). It is characterized by external ophthalmoplegia, ataxia, and areflexia. The incidence of MFS as a proportion of GBS was reported to be 1 to 5 % in western countries and considerably higher in Eastern Asia i.e. 19% in Taiwan and 25% in Japan. Here we report the clinical features of a patient who initially presented with ataxia then subsequently developed limb weakness, areflexia and ophthalmoplegia. CSF study and NCV study supported our clinical diagnosis. Patient was managed conservatively. No intravenous immunoglobulin was given but the patient gradually improved in symptoms including power, ataxia, ophthalmoparesis. After one month the patient was discharged from hospital with complete recovery.

DOI: http://dx.doi.org/10.3329/bsmmuj.v5i1.11028

BSMMU J 2012; 5(1):69-71

 

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Abstract
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Published
2012-06-29
How to Cite
Das, P., Biswash, S., Karim, M., Ahmed, N., Islam, B., Mandal, S., & Sarkar, A. (2012). Miller Fisher Variant of Guillain-Barré Syndrome: A Case Report & Clinical Review. Bangabandhu Sheikh Mujib Medical University Journal, 5(1), 69-71. https://doi.org/10.3329/bsmmuj.v5i1.11028
Section
Case Reports