Time-dependent biochemical response after middle cerebral artery occlusion in rats: A pilot study

Authors

  • Asma Parveen Department of Neuroscience Physiotherapy, Abhinav Bindra Sports Medicine and Research Institute, Bhubaneswar, India https://orcid.org/0000-0003-2622-4101
  • Prathap Suganthirababu Department of Neurology Physiotherapy, Saveetha College of Physiotherapy, Saveetha Institute of Medical and Technical Sciences, Chennai, India
  • Lavanya Prathap Department of Anatomy, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, Chennai, India
  • Ashisha Kshirabdhi Tanaya Department of Neurology Physiotherapy, Hi-Tech College of Physiotherapy, Hi-Tech Medical College and Hospital, Odisha, India
  • Yamini Umasankar Department of Neurology Physiotherapy, Saveetha College of Physiotherapy, Saveetha Institute of Medical and Technical Sciences, Chennai, India
  • Debadutta Patra Department of Neurology Physiotherapy, Alva’s College of Physiotherapy and Research Centre, Karnataka, India https://orcid.org/0009-0002-9217-7497

Keywords:

ischemic stroke, middle cerebral artery occlusion, oxidative stress, inflammation

Abstract

Not available

Abstract
36
Article text
8 PDF
19 Review report
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Author Biography

Prathap Suganthirababu , Department of Neurology Physiotherapy, Saveetha College of Physiotherapy, Saveetha Institute of Medical and Technical Sciences, Chennai, India

Prathap Suganthirababu, Ph.D.

Professor and Principal, Saveetha College of Physiotherapy, Saveetha Institute of Medical and Technical Sciences, Chennai, India

ORCID ID: 000-0002-1419-266X

Email: emailprathap@gmail.com

References

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Trotman-Lucas M, Gibson CL. A review of experimental models of focal cerebral ischemia focusing on the middle cerebral artery occlusion model. F1000Research. 2021;10:242. doi: https//doi.org/10.12688/f1000research.51573.1

Sokolowski JD, Soldozy S, Sharifi KA, Norat P, Kearns KN, Liu L, Williams AM, Yagmurlu K, Mastorakos P, Miller GW, Kalani MYS, Park MS, Kellogg RT, Tvrdik P. Preclinical models of middle cerebral artery occlusion: new imaging approaches to a classic technique. Front Neurol. 2023;14:1170675. doi: https//doi.org/10.3389/fneur.2023.1170675

Rehman S, Nadeem A, Akram U, Sarwar A, Quraishi A, Siddiqui H, Malik MAJ, Nabi M, Ul Haq I, Cho A, Mazumdar I, Kim M, Chen K, Sepehri S, Wang R, Balar AB, Lakhani DA, Yedavalli VS. Molecular mechanisms of ischemic stroke: a review integrating clinical imaging and therapeutic perspectives. Biomedicines. 2024;12(4):812. doi: https//doi.org/10.3390/biomedicines12040812

Domingues A, Fantin A. Neuropilin 1 regulation of vascular permeability signaling. Biomolecules. 2021;11(5):666. doi: https//doi.org/10.3390/biom11050666

Pawluk H, Woźniak A, Tafelska-Kaczmarek A, Kosinska A, Pawluk M, Sergot K, Grochowalska R, Kołodziejska R. The role of IL-6 in ischemic stroke. Biomolecules. 2025;15(4):470. doi: https//doi.org/10.3390/biom15040470

Meng X, Zheng Z, Yang L, Yang C, Li X, Hao Y. Dynamic mechanisms and targeted interventions in cerebral ischemia–reperfusion injury: pathological cascade from ischemia to reperfusion and promising therapeutic strategies. Front Neurosci. 2025;19:1649533. doi: https//doi.org/10.3389/fnins.2025.1649533

Wu L, Xiong X, Wu X, Ye Y, Jian Z, Zhi Z, Gu L. Targeting oxidative stress and inflammation to prevent ischemia-reperfusion injury. Front Mol Neurosci. 2020;13:28. doi: https//doi.org/10.3389/fnmol.2020.00028

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Published

02-08-2026

How to Cite

Parveen, A., Suganthirababu , P., Prathap, L., Tanaya, A. K. ., Umasankar, Y., & Patra, D. (2026). Time-dependent biochemical response after middle cerebral artery occlusion in rats: A pilot study. Bangabandhu Sheikh Mujib Medical University Journal, 19(3), e88535. https://doi.org/10.3329/bsmmuj.v19i3.88535

Issue

Vol. 19 No. 3 (2026): July - Sep

Section

Research Letter

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Copyright (c) 2026 Asma Parveen, Prathap Suganthirababu , Lavanya Prathap, Ashisha Kshirabdhi Tanaya, Yamini Umasankar, Debadutta Patra

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

How to Cite

Parveen, A., Suganthirababu , P., Prathap, L., Tanaya, A. K. ., Umasankar, Y., & Patra, D. (2026). Time-dependent biochemical response after middle cerebral artery occlusion in rats: A pilot study. Bangabandhu Sheikh Mujib Medical University Journal, 19(3), e88535. https://doi.org/10.3329/bsmmuj.v19i3.88535