Incidence of anti-HBc antibody (IgG and IgM) among HBsAg negative apparently healthy blood donors

  • Nittyananda Shil Department of Transfusion Medicine, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka
  • Jolly Biswas Department of Transfusion Medicine, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka
  • Ayesha Khatun Department of Transfusion Medicine, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka
  • Atiar Rahman Department of Transfusion Medicine, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka
  • Nahid Sultana Department of Transfusion Medicine, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka
  • Fatema Easmin Department of Transfusion Medicine, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka
  • Sonia Sormin Department of Transfusion Medicine, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka
Keywords: Anti-HBc antibody, Blood donor, HBsAg, IgG, IgM

Abstract

In person who is unable to produce HBsAg, anti-HBc antibody is a helpful marker of hepatitis B virus (HBV) infection. In the present study, we have tried to find out the incidence of anti-HBc (IgG and IgM) among blood donors HBsAg negative. People came for donating blood voluntarily or for their relatives (n = 1000) was selected on inclusion and exclusion criteria. Purposefully selected and collated samples were first tested by HBsAg ELISA of third generation reagent. HBsAg negative sample was tested with anti-HBc ELISA. Positive found in the first test was retested. Out of 1,000 samples on duplicate test, 117 positives were detected. The incidence of anti-HBc antibody among apparently healthy blood donors was found 11.7%.

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Author Biography

Nittyananda Shil, Department of Transfusion Medicine, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka

 

 

Published
2016-12-05
How to Cite
Shil, N., Biswas, J., Khatun, A., Rahman, A., Sultana, N., Easmin, F., & Sormin, S. (2016). Incidence of anti-HBc antibody (IgG and IgM) among HBsAg negative apparently healthy blood donors. Bangabandhu Sheikh Mujib Medical University Journal, 9(4), 201-204. https://doi.org/10.3329/bsmmuj.v9i4.30241
Section
Original Articles