Contrast Induced Nephropathy and Gender Variation

Authors

  • Md Abu Siddique Department of Cardiology, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Bikash Subedi Department of Cardiology, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Jahanara Arzu Department of Cardiology, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Quazi Arif Ahmed Department of Cardiology, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Anisul Awal Department of Cardiology, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Dilip Kumar Sarker Department of Cardiology, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Md Sirajul Islam Department of Cardiology, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Md Mukhlesur Rahman Department of Cardiology, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Md Khursed Ahmed Department of Cardiology, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Nilufar Fatema Department of Cardiology, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Md Ashraf Uddin Sultan Department of Cardiology, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • SM Mustafa Zaman Department of Cardiology, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Md Harisul Hoque Department of Cardiology, Bangabandhu Sheikh Mujib Medical University, Dhaka

DOI:

https://doi.org/10.3329/uhj.v6i1.7184

Keywords:

Contrast-induced nephropathy, Percutaneous interventions, Serum Creatinine

Abstract

Contrast-induced nephropathy (CIN) is a recognized complication after percutaneous interventions (PCI). We sought to determine the impact of gender on incidence of CIN. Of a total 200 patients who underwent PCI, there were 33 (16.5%) who developed CIN (defined as > 25% rise in creatinine after PCI). CIN was present in 23.6% of female versus 17.4% of male patients (p < 0.0001). Multivariate analysis showed that female gender (p < 0.0001), pre-PCI chronic renal failure (CRF) (OR= 1.8, 95% CI = 1.53a€"2.10, p < 0.0001), diabetes mellitus (OR = 1.5, 95%, p < 0.0001), age (OR = 1.01, p < 0.0001), and hypertension (OR = 1.2, p = 0.0035) were independent predictors of CIN. By multivariate analysis only baseline CRF, diabetes, age, functional NYHA IV class were identified as independent risk factor for CIN. Female gender is an independent predictor of CIN development.

Key words: Contrast-induced nephropathy; Percutaneous interventions; Serum Creatinine.

DOI: 10.3329/uhj.v6i1.7184

University Heart Journal Vol.6(1) 2010 pp.18-20

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How to Cite

Siddique, M. A., Subedi, B., Arzu, J., Ahmed, Q. A., Awal, A., Sarker, D. K., Islam, M. S., Rahman, M. M., Ahmed, M. K., Fatema, N., Sultan, M. A. U., Zaman, S. M., & Hoque, M. H. (2011). Contrast Induced Nephropathy and Gender Variation. University Heart Journal, 6(1), 18–20. https://doi.org/10.3329/uhj.v6i1.7184

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Original Articles