Isolation of mouse internal organs for molecular and histopathological studies

Authors

DOI:

https://doi.org/10.3329/bjp.v11i2.26957

Keywords:

Mouse, Organ isolation

Abstract

Since autoimmune diseases dramatically affect function of various tissues and organs in vivo, each integral organ of mouse has significant value in order to analyze the effect of any pharmaceuticals or test drugs to confirm their protective efficacy. Hence, this study reports step-by-step visual demonstration of isolation of various internal tissue organs such as liver, spleen, adipose tissue, muscles, and pancreas from mouse model which have significant contribution to design in-depth molecular level studies along with histomorphological evidences that may assist research to set innovative results at molecular level, thus may help to prove the efficacy of any test sample as a new drug of pharmaceutical importance.

Video Clip of Methodology:

Isolation of organs: 7 min 55 sec   Full Screen   Alternate

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Author Biographies

Vivek K. Bajpai, Department of Applied Microbiology and Biotechnology, Yeungnam University, Gyeongsan 712-749

Assistant Professor

Google Scholar Citation Index

Irfan A. Rather, Department of Applied Microbiology and Biotechnology, Yeungnam University, Gyeongsan 712-749

Assistant Professor

Google Scholar Citation Index

References

Bajpai VK, Rather I, Nam GJ. Experimental strategy of animal trial for the approval of antidiabetic agents prior to their use in pre-human clinical trials. Bangladesh J Pharmacol. 2016; 11: 30-34.

Deng Y, Zhang Y, Lu Y, Z Y, Ren H. Hepatotoxicity and nephrotoxicity induced by the chlorpyrifos and chlorpyrifos-methyl metabolite, 3,5,6-trichloro-2-pyridinol, in orally exposed mice. Sci Tot Environ. 2016; 544: 507-14.

Haenen S, Clynen E, Nemery B, Hoet PHM, Vanoirbeek JAJ. Biomarker discovery in asthma and COPD: Application of proteomics techniques in human and mice. Eupa Open Proteom. 2014; 4: 101-12.

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Published

2016-04-16

How to Cite

Bajpai, V. K., I. A. Rather, and K. Kim. “Isolation of Mouse Internal Organs for Molecular and Histopathological Studies”. Bangladesh Journal of Pharmacology, vol. 11, no. 2, Apr. 2016, pp. 485-8, doi:10.3329/bjp.v11i2.26957.

Issue

Section

Visual Experiment