Influence of Nano-Methionine supplementation in drinking water on growth performance, lipid metabolism, and related gene expression in broiler chicken

Authors

  • Set A El Shobokshy Department of Nutrition and Veterinary Clinical Nutrition, Faculty of Veterinary Medicine, Alexandria University, Alexandria, Egypt.
  • Magda I Abo Samaha Poultry Breeding and Production, Department of Animal Husbandry and Animal Wealth Development, Faculty of Veterinary Medicine, Alexandria University, Alexandria, Egypt. https://orcid.org/0000-0002-8011-554X
  • Eman M Abd El Maksoud Biochemistry Department, Faculty of Veterinary Medicine, Alexandria University, Alexandria, Egypt.
  • Shymaa A Khatab Genetics and Genetic Engineering, Department of Animal Husbandry and Animal Wealth Development, Faculty of Veterinary Medicine, Alexandria University, Alexandria, Egypt.
  • Asmaa F Khafaga Pathology Department, Faculty of Veterinary Medicine, Alexandria University, Alexandria, Egypt.
  • Gemechu Wirtu Department of Biomedical Sciences, College of Veterinary Medicine, Tuskegee University, Tuskegee, AL, USA.

Keywords:

Broiler; Nano-Methionine; growth performance; lipid; gene expression; histopathology

Abstract

Objectives: The study aimed to determine how Nano-Methionine (Nano-Meth) affected growth, lipid metabolism, and relative gene expression for acetyl-CoA carboxylase (ACC), fatty acid synthase (FAS), growth hormone receptor (GHR), insulin-like growth factor receptor-1 (IGFR-1), myostatin (MSTN), and cholecystokinin (CCK) genes in broiler chickens. Materials and Methods: A total of 100 1-day-old broilers were randomly assigned into 2 groups: 1) the control group received drinking water without any supplements, and 2) the Nano-Meth group received 10 ml/l of 5% Nano-Meth starting from 1 day old until 35 days old (the end of the experiment). Results: Nano-Meth improved final body weight, weight gains, feed intake, and feed conversion ratio. Compared to the control group, Nano-Meth significantly lowered the serum levels of triglyceride, cholesterol, very low-density lipoprotein, and low-density lipoprotein in chickens. Nano-Meth significantly increased the serum levels of total protein, albumin, high-density lipoprotein, and glucose more than the control group. Nano-Meth lowered the mRNA gene expression of ACC, FAS, MSTN, and CCK but increased that of GHR and IGFR-1. Conclusions: We concluded that supplementation with Nano-Meth enhances growth performance and decreases lipid accumulation in broiler chickens.

J. Adv. Vet. Anim. Res., 9(4): 743–753, December 2022

http://doi.org/10.5455/javar.2022.i644

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Published

2022-12-31

How to Cite

El Shobokshy, S. A., Abo Samaha, M. I., El Maksoud, E. M. A., Khatab, S. A., Khafaga, A. F., & Wirtu, G. (2022). Influence of Nano-Methionine supplementation in drinking water on growth performance, lipid metabolism, and related gene expression in broiler chicken. Journal of Advanced Veterinary and Animal Research, 9(4), 743–753. Retrieved from https://www.banglajol.info/index.php/JAVAR/article/view/80277

Issue

Vol. 9 No. 4 (2022)

Section

Original Articles

License

Copyright (c) 2022 Set A El-Shobokshy, Magda I Abo-Samaha, Eman M Abd El-Maksoud, Shymaa A Khatab, Asmaa F Khafaga, Gemechu Wirtu

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