The effects of anesthetic drug choice on heart rate variability in dogs

  • Nakrob Pattanapon
  • Ratikorn Bootcha
  • Soontaree Petchdee

Abstract

Objective: The objective of this study was to assess the effects of anesthetic drugs on heart rate (HR) and heart rate variability (HRV) in dogs.

Materials and Methods: Twelve healthy client-owned dogs of various breeds, including five females and seven males were used for elective surgery in this study. The dogs were pre-medicated with four protocols; (1) alfaxalone [at 3 mg/kg body weight (bwt)], (2) zolazepam + tiletamine (Zoletil) (at 5 mg/kg bwt), (3) diazepam (at 0.3 mg/kg bwt) + ketamine (at 5 mg/kg bwt), and (4) diazepam (at 0.3 mg/kg bwt) + propofol (at 5 mg/kg bwt). The HR and HRV of 12 dogs were recorded 20 min before and after the administration of the anesthetic drugs. Doppler was used to obtain systolic, diastolic, and mean blood pressures.

Results: After anesthetic drug administration, the dogs pre-medicated and inducted with alfaxalone had the lowest HR values as compared with those of other protocols. The HRV low frequency and high frequency power ratio decreased in the dogs pre-medicated and intubated with alfaxalone.

Conclusion: This study demonstrates that alfaxalone preserves the cardiovascular function; and hence, is considered as safe to use for the surgical applicability in dogs.

http://doi.org/10.5455/javar.2018.e303

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Author Biographies

Nakrob Pattanapon

Faculty of Veterinary Medicine, Kasetsart University Veterinary Teaching Hospital, Kasetsart University, Kamphaeng Saen Campus, Bangkok 73140 Thailand

Ratikorn Bootcha

Faculty of Veterinary Medicine, Kasetsart University Veterinary Teaching Hospital, Kasetsart University, Kamphaeng Saen Campus, Bangkok 73140 Thailand

Soontaree Petchdee

Department of Large Animal and Wildlife Clinical Sciences, Faculty of Veterinary Medicine, Kasetsart University, Kamphaeng Saen Campus, Bangkok 73140, Thailand

Published
2018-12-29
How to Cite
Pattanapon, N., Bootcha, R., & Petchdee, S. (2018). The effects of anesthetic drug choice on heart rate variability in dogs. Journal of Advanced Veterinary and Animal Research, 5(4), 485-489. Retrieved from https://www.banglajol.info/index.php/JAVAR/article/view/39516
Section
Short Communications