Determination of lowest immune protective titer against Salmonella gallinarum and Salmonella pullorum in chicken vaccinated with BAU-Salmonella bivalent vaccine

  • Eusha Islam
  • Rajib Saha
  • Md. Golzar Hossain
  • Shah Md. Abdur Rauf
  • Md. Mansurul Amin
  • Sukumar Saha
Keywords: Antibody, PHA test, Salmonella vaccine, Titer, Vaccination

Abstract

Objective: The research work was conducted to determine the duration of protective efficacy and lowest immune protective titer of Salmonella bivalent vaccine containing Salmonella gallinarum and Salmonella pullorum prepared at the Livestock and Poultry Vaccine Research and Production Centre (LPVRPC) of Bangladesh Agricultural University (BAU), Mymensingh, Bangladesh.

Materials and methods: The experimental chickens were subdivided into four main groups (A, B, C and D). Group A and B were vaccinated with BAU-Salmonella bivalent vaccine with dosed 0.5 mL intramuscularly at the age of seven weeks followed by a booster vaccination at 12 weeks of age while group C and D served as unvaccinated control. The sera samples were obtained at 7, 12, 15, 18, 23, 27, 30, 32, 34, 36 and 41 weeks of age of birds.

Results: Significantly elevated level of immune response in terms of antibody production resulted from booster vaccination. Vaccinated chicken showed protective resistance following virulent challenge with isolates of S. gallinarum and S. pullorum (**P<0.01) till 41 weeks, whereas unvaccinated control birds failed to resist the virulent challenge infection.

Conclusion: BAU-Salmonella bivalent vaccine showed lowest immune protective titer up to seven months following booster vaccination.

http://doi.org/10.5455/javar.2018.e278  

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Author Biographies

Eusha Islam

Department of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh.

Rajib Saha
Department of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh.
Md. Golzar Hossain
Department of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh.
Shah Md. Abdur Rauf

Department of Veterinary and Animal Sciences, Rajshahi University, Rajshahi-6210, Bangladesh.

Md. Mansurul Amin

Department of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh.

Sukumar Saha
Department of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh.
Published
2018-10-02
How to Cite
Islam, E., Saha, R., Hossain, M. G., Rauf, S. M. A., Amin, M. M., & Saha, S. (2018). Determination of lowest immune protective titer against Salmonella gallinarum and Salmonella pullorum in chicken vaccinated with BAU-Salmonella bivalent vaccine. Journal of Advanced Veterinary and Animal Research, 5(3), 282-289. Retrieved from https://www.banglajol.info/index.php/JAVAR/article/view/38433
Section
Original Articles