Enhancing Skin Health: The Role of Nutraceutical Synergies in Counteracting the Signs of Aging

Authors

  • Lim Chin Chuan Physician, Medical Director, Clinic Pelangi, Kuala Ketil, Kedah, Malaysia
  • Lim Chin Choon Associate Professor, Pharmacology Unit, Faculty of Medicine, Widad University College (WUC), Kuantan, Malaysia
  • Hasbullani Zakaria Deputy Vice Chancellor (Research and Postgraduate), Biochemistry Unit, Faculty of Medicine, WUC, Kuantan, Malaysia
  • Elamin Mohamed Elamin Mohamed Microbiology Unit, Faculty of Medicine, WUC, Kuantan, Malaysia
  • Muhd Khairi Bin Mohd Taibi Deputy Dean (Student Affairs). Family Medicine Unit, Faculty of Medicine, WUC, Kuantan, Malaysia
  • Abdus Salam Associate Professor, Medical Education Unit, Faculty of Medicine, WUC, Kuantan, Malaysia
  • Jamaludin Bin Zainol Professor of Surgery, Deputy Vice Chancellor (Academic and Internationalization), and Dean Faculty of Medicine, WUC, Kuantan, Malaysia

DOI:

https://doi.org/10.3329/bjms.v24i4.84670

Keywords:

Skin health, Aging, Nutraceutical, Counteracting skin sign in aging

Abstract

Skin is the largest organ of the human body which is affected by aging. The objective of this review paper is to briefly highlights the factors responsible for skin changes in aging and the role of nutraceutical synergies in counteracting the signs of aging. Ageing is a multifaceted biological process impacting skin health through intrinsic genetic programming and extrinsic environmental factors. Intrinsic ageing, characterized by hormonal changes and fibroblast dysfunction, and extrinsic factors, such as reactive oxygen species and advanced glycation end-products, compromise skin structure and function. Modern lifestyles, including poor nutrition, environmental pollutants, and UV exposure exacerbate oxidative stress and accelerate skin ageing. Nutraceutical interventions demonstrate significant potential in mitigating these effects, including collagen peptides, hyaluronic acid, nicotinamide mononucleotide, and trace elements like zinc and copper. These bioactive compounds promote collagen synthesis, enhance hydration, and reduce oxidative stress, improving skin elasticity, hydration, and resilience. This study emphasizes the efficacy of a multi-nutraceutical approach, which synergistically addresses ageing pathways, providing a promising avenue for personalized, effective anti-ageing strategies. Future research is recommended to focus on long-term, populationdiverse studies to validate these findings and expand their applicability.

BJMS, Vol. 24 No. 04 October’25 Page : 1072-1078

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Published

2025-11-02

How to Cite

Chuan, L. C., Choon, L. C., Zakaria, H., Elamin Mohamed, E. M., Mohd Taibi, M. K. B., Salam, A., & Zainol, J. B. (2025). Enhancing Skin Health: The Role of Nutraceutical Synergies in Counteracting the Signs of Aging. Bangladesh Journal of Medical Science, 24(4), 1072–1078. https://doi.org/10.3329/bjms.v24i4.84670

Issue

Vol. 24 No. 4 (2025)

Section

Review Article

License

Copyright (c) 2025 Lim Chin Chuan, Lim Chin Choon, Hasbullani Zakaria, Elamin Mohamed Elamin Mohamed, Muhd Khairi Bin Mohd Taibi, Abdus Salam, Jamaludin Bin Zainol

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