Association between serum albumin and disease severity of non-cystic fibrosis bronchiectasis
DOI:
https://doi.org/10.3329/bjms.v23i4.76524Keywords:
Non-cystic fibrosis bronchiectasis; Serum albumin; Bronchiectasis severity indexAbstract
Background Bronchiectasis is a chronic debilitating but neglected pulmonary disease. It is associated with substantial health related burden and health care costs. However, the biochemical parameters related to disease severity have not been sufficiently assessed. Objective: Aim of the present study to find out any association between serum albumin and disease severity of non-cystic fibrosis bronchiectasis. Methods This was a cross-sectional observational study of 33 subjects with non-cystic fibrosis bronchiectasis at department of Respiratory Medicine, National Institute of Diseases of the Chest and Hospital (NIDCH) from December 2019 to March 2021. After taking informed written consent BSI score be calculated and blood was taken for to measure serum albumin. Data was collected through questionnaire. After completion of the data collection, analysis was done with the help of Statistical Package for Social Science (SPSS) version 22. Results Mean age of the study subjects was 43.36 ± 15.65 years with a range of 21 -76 years and more likely to be men (60.6%). History of previous pulmonary tuberculosis found in 48.5% subjects as associated conditions and pseudomonas aeruginosa (21.2%) was the most common organisms in sputum culture. 87.9% of the study subjects had history of exacerbation within last 12 months and 60.6% were hospitalized within last 2 years. More than half (54.6%) of the study subjects had severe, 33.3% had moderate and 12.1% had mild bronchiectasis with the mean BSI score of 9.00 ± 3.05. Mean serum albumin was 3.22 ± 0.84 g/dl. Albumin had a significant negative correlation with BSI score (r = -0.457 and p = 0.008). Conclusion The serum albumin had moderate correlation with disease severity of non-cystic fibrosis bronchiectasis.
Bangladesh Journal of Medical Science Vol. 23 No. 04 October’24 Page : 1104-1111
Downloads
19
17
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Shaifuddin Mohammad Khaled, Mahmud Rahim, Mohammed Jamil Reza Choudhury, Leema Saha, Shamima Nasrin, Bibi Hajera
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish in the Bangladesh Journal of Medical Science agree to the following terms that:
- Authors retain copyright and grant Bangladesh Journal of Medical Science the right of first publication of the work.
Articles in Bangladesh Journal of Medical Science are licensed under a Creative Commons Attribution 4.0 International License CC BY-4.0.This license permits use, distribution and reproduction in any medium, provided the original work is properly cited.- Authors are able to enter into separate, additional contractual arrangements for the distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted to post their work online (e.g., in institutional repositories or on their website) as it can lead to productive exchanges, as well as greater citation of published work.