Predictors of Post-Operative Acute Kidney Injury in relation with N-Terminal Pro-B-Type Natriuretic Peptide Level among Patients Undergoing Mitral Valve Replacement

Authors

  • Md Tanvir Hossain Assistant Register, Department of Cardiac Surgery, National Institute of Cardiovascular Diseases, Dhaka, Bangladesh
  • Asraful Hoque Associate Professor, Department of Cardiac Surgery, National Institute of Cardiovascular Diseases, Dhaka, Bangladesh
  • Tasmin Rubayath Medical Officer, Department of Clinical Pathology; Dhaka Medical College Hospital; Dhaka, Bangladesh;
  • Romena Rahman Assistant Professor, Department of Cardiac Surgery, National Institute of Cardiovascular Diseases, Dhaka, Bangladesh
  • Abu Shadat Mohammad Saem Khan Assistant Register, Department of Cardiac Surgery, National Institute of Cardiovascular Diseases, Dhaka, Bangladesh
  • Md Noor-E-Elahi Mozumder Assistant Register, Department of Cardiac Surgery, National Institute of Cardiovascular Diseases, Dhaka, Bangladesh
  • Md Monzur Hossain Assistant Register, Department of Cardiac Surgery, National Institute of Cardiovascular Diseases, Dhaka, Bangladesh
  • Imran Ahmed Assistant Register, Department of Cardiac Surgery, National Institute of Cardiovascular Diseases, Dhaka, Bangladesh
  • Muhammad Asif Ahsan Chowdhury Assistant Register, Department of Cardiac Surgery, National Institute of Cardiovascular Diseases, Dhaka, Bangladesh
  • Wahida Salam Assistant Register, Department of Cardiac Surgery, National Institute of Cardiovascular Diseases, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/jcamr.v8i2.57430

Keywords:

acute kidney injury; N-terminal Pro-B-type natriuretic peptide; mitral valve replacement

Abstract

Background: The N-terminal Pro-B-type natriuretic peptide (NT-proBNP) level can be utilized as post-operative prediction models suring cardiac surgery.

Objective: The objective was to find out the predictors of post-operative acute kidney injury in relation with N-Terminal Pro-B-Type natriuretic peptide level among mitral valve replacement patients.

Methodology: This cross-sectional study was conducted in the Department of Cardiac Surgery at National Institute of Cardiovascular Diseases, Dhaka, Bangladesh from January 2018 to December 2019. Patients with the age of more than or equal to 18 years with both sexes who were underwent mitral valve replacement were selected as study population. Patients were divided into two groups based on pre-operative NT-proBNP level. Post-operatively patients were observed on the basis of post-operative serum creatinine.

Results: A total number of 100 patients were recruited for this study of which 50 cases were in group A and the rest of 50 cases were in the group B. Elevated NT-proBNP was the most powerful and independent pre-operative variable in predicting post-operative AKI development (OR 0.999, 95% CI 0.998-1.00) Conclusion: In conclusion elevated NT-proBNP is the most powerful and independent pre-operative variable in predicting post-operative acute kidney injury.

Journal of Current and Advance Medical Research, July 2021;8(2):85-89

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Published

2021-07-01

How to Cite

Hossain, M. T. ., Hoque, A. ., Rubayath, T. ., Rahman, R. ., Saem Khan, A. S. M., Mozumder, M. N.-E.-E. ., Hossain, M. M. ., Ahmed, I. ., Ahsan Chowdhury, M. A. ., & Salam, W. (2021). Predictors of Post-Operative Acute Kidney Injury in relation with N-Terminal Pro-B-Type Natriuretic Peptide Level among Patients Undergoing Mitral Valve Replacement. Journal of Current and Advance Medical Research, 8(2), 85–89. https://doi.org/10.3329/jcamr.v8i2.57430

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