Factors Associated with Multidrup-Resistant Tuberculosis

  • Md Nurul Amin GSO-II, R & P, Armed Forces Medical Institute, Dhaka Cantonment, Dhaka
  • Md Anisur Rahman Dept of Epidemiology, National Institute of Preventive & Social Medicine (NIPSOM), Dhaka
  • Meerjady Sabrina Flora Dept of Epidemiology, National Institute of Preventive & Social Medicine (NIPSOM), Dhaka
  • Md Abul Kalam Azad GSO-II, R & P, Armed Forces Medical Institute, Dhaka Cantonment, Dhaka
Keywords: Tuberculosis, MDR TB

Abstract

This case control study was conducted in selected centers of Dhaka City from March to July 2008 to determine the association of multidrug-resistant tuberculosis with the attributes related to treatment and socio-economic condition of tuberculosis patients. Sixty seven culture-proven multidrug-resistant tuberculosis cases and similar number of age and sex matched controls were selected purposively. Data were collected by face to face interview and documents' review, using a pre tested structured questionnaire and a checklist. Multidrug-resistance was found to be associated with occupation (p=0.001) and residential status (p=0.001) of the tuberculosis patients. Tuberculosis patients who did not remain under directly observed treatment were 3 times more likely to develop multidrugresistant tuberculosis (OR 3.21, 95%CI=1.59-6.52). Multidrug-resistance was associated with inadequacy of treatment (OR 2.56, 95%CI=2.03-3.23). Failure of sputum conversion at the end of 2 months of treatment was detected to be the best predictor of multidrug-resistant tuberculosis (OR 11.82, 95% CI=4.61-30.33), followed by treatment with non Directly Observed Treatment Short course regimen and high labor intensive occupations like agriculture, production and transport. The risk factors of multidrug-resistant tuberculosis warrant much improvement in the effective implementation of control programs.

Ibrahim Med. Coll. J. 2009; 3(1): 29-33

Key wards: Tuberculosis, MDR TB.  

doi: 10.3329/imcj.v3i1.2917   

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Author Biography

Md Nurul Amin, GSO-II, R & P, Armed Forces Medical Institute, Dhaka Cantonment, Dhaka
Major Md Nurul Amin, GSO-II, R & P, Armed Forces Medical Institute, Dhaka Cantonment, Dhaka.
How to Cite
Amin, M., Rahman, M., Flora, M., & Azad, M. (1). Factors Associated with Multidrup-Resistant Tuberculosis. Ibrahim Medical College Journal, 3(1), 29-33. https://doi.org/10.3329/imcj.v3i1.2917
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Original Articles