Association between Serum Total Cholesterol and Cigarette Smoking among Adult Male population of Mymensingh District, Bangladesh

Abstract

Cigarette smoking is one of the most widespread potentially harmful social habits practiced worldwide. A cross-sectional, comparative study was conducted in the Department of Physiology, Mymensingh Medical College, Bangladesh, and the Mymensingh locality, between July 2014 and June 2015, to determine the effect of smoking on serum total cholesterol levels among male smokers. A total of 150 adult males participated in this study recruited from outpatient department of Mymensingh Medical College Hopspital hailing from different parts of Mymensingh district. Among them, apparently healthy 50 non-smokers were considered as control in group-I, while the other 100 cigarette smokers (smoking ≥20 cigarettes per day) were divided equally into two sub-groups, as group-IIA (5-10 years duration of smoking) and group-IIB (having history of >10 years of smoking). We adopted a purposive, non-randomized sampling method. A semi-structured questionnaire including sociodemographic data and habits of smoking was completed by all study participants. Serum total cholesterol level was measured by enzymatic hydrolysis and oxidation method. There was no significant difference regarding the mean age and BMI of the participants in different groups (p<0.05). However, the mean systolic and diastolic blood pressure were increased gradually with duration of smoking in comparison to control (group-I), which was statistically significant (p<0.001); however, all the values were within physiological limits. The mean serum total cholesterol levels 152.28±1.22 mg/dL, 190.8±1.71 mg/dL, and 190.28±1.71 mg/dL in group-I, group-IIA, and group-IIB, respectively. Serum total cholesterol levels were found increased in both group-IIA and group-IIB compared to control (group-I). The differences were statistically significant (p<0.05). Serum total cholesterol level also found a bit higher in group-IIB compared to group-IIA. However, the difference was not statistically significant (p>0.05). Our study shows that cigarette smoking has a strong effects that is reflected through increase serum total cholesterol levels with the duration of smoking.

  CBMJ 2026 July: Vol. 15 No. 02 P:380-384