Diuretic effect of Caesalpinia bonduc in rats

  • Ajay Khedkar Department of Pharmacognosy and Phytochemistry, KLEUs College of Pharmacy, Belgaum
  • Yuvaraj D. Mandavkar Department of Pharmacognosy and Phytochemistry, KLEUs College of Pharmacy, Belgaum
  • Gulab Shinde Department of Pharmacognosy and Phytochemistry, KLEUs College of Pharmacy, Belgaum
  • Pallavi Khalure Department of Pharmacognosy and Phytochemistry, KLEUs College of Pharmacy, Belgaum
  • Pravin Dere Department of Pharmacognosy and Phytochemistry, KLEUs College of Pharmacy, Belgaum
Keywords: Caesalpinia bonduc, Diuretic, Herbal, Medicinal plant

Abstract

The diuretic effect of aqueous and methanol extracts of the dried seeds of Caesalpinia bonduc was studied in normal rats. Extracts were administered orally at two doses and furosamide was used as standard drug. Urine volume was significantly increased by the two doses of aqueous and methanol extracts in comparison to control group. While the excretion of sodium was also increased by both extracts, potassium excretions were only increased by the aqueous and methanol extracts at a higher dose. The present study provides a quantitative basis for explaining the use of seeds extracts of C. bonduc as a diuretic agent.

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Published
2011-09-20
How to Cite
Khedkar, A., Y. Mandavkar, G. Shinde, P. Khalure, and P. Dere. “Diuretic Effect of Caesalpinia Bonduc in Rats”. Bangladesh Journal of Pharmacology, Vol. 6, no. 1, Sept. 2011, pp. 61-63, doi:10.3329/bjp.v6i1.8487.
Section
Research Articles