Antiprotozoal activities of Vincetoxicum stocksii and Carum copticum

  • Arsala Mansoor Department of Pharmacognosy, School of Pharmacy, University of Mississippi
  • Mohammad Ali Ibrahim Department of Pharmacognosy, School of Pharmacy, University of Mississippi
  • Mudassir Asrar Zaidi Department of Botany, University of Balochistan, Quetta
  • Moinuddin Ahmed Department of Botany, University of Balochistan, Quetta
Keywords: Antileishmanial, Antimalarial, Carum copticum, Vincetoxicum stocksii

Abstract

The antileishmanial and antimalarial activities of different fractions of Vincetoxicum stocksii, Carum copticum, Gentiana olivierii and Zygophyllum fabago were determined.  Amongst these, V. stocksii and C. copticum showed moderate to good antimalarial activity. The ethyl acetate fractions of C. copticum and hexane fraction of V. stocksii showed 94 % and 52% inhibition of Plasmodium falciparum (D6 Clone) respectively. The hexane ethyl acetate fraction of C. copticum and  V. stocksi exhibited antileishmanial activity against, Leishmania donovani promastigotes with IC50 of 30 µg/mL and 51 mg/mL, respectively.

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Published
2011-09-09
How to Cite
Mansoor, A., M. Ibrahim, M. Zaidi, and M. Ahmed. “Antiprotozoal Activities of Vincetoxicum Stocksii and Carum Copticum”. Bangladesh Journal of Pharmacology, Vol. 6, no. 1, Sept. 2011, pp. 51-54, doi:10.3329/bjp.v6i1.8442.
Section
Research Articles