Serum iron and total iron binding capacity in severely malnourished children


  • Md. Atiar Rahman Department of Pediatrics, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka
  • M. A. Mannan Department of Pediatrics, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka
  • Md. Hamidur Rahman Department of Pediatrics, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka



Iron, Malnourished children, Plasma protein, Total iron binding capacity


Serum iron, total iron binding capacity and plasma protein of severely malnourished children of 12-59 months of age were compared with that of normal healthy children. Mean serum total protein and albumin level in normal children were 76.33 ± 0.51, 43.50 ± 0.38 gm/L respectively which was significantly higher (p<0.05) than that of malnourished children (64.39 ± 0.57, 30.17 ± 0.45 gm/L). But mean serum globulin level was (34.22 ± 0.27 gm/l) higher in malnourished children than that of normal children (32.83 ± 0.53 gm/L). The mean serum iron and transferrin saturation level were (78.72 ± 11.12 µg/dL, 23.38 ± 1.97%) significantly high (p<0.001) in severely malnourished children than in normal children, whereas serum TIBC had no significant difference between these two groups.



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Bangladesh Bureau of Statistics (BBS) and United Nations International Children Emergency Fund (UNICEF). Child nutrition survey in Bangladesh. 2000, p 41.

Begum T, Islam MN. Study on serum iron, total iron binding capacity in hospitalized PEM children. Bangladesh J Child Health. 1996; 20: 77-82.

Dallman PR. Iron deficiency and the immune response. Am J Clin Nutr. 1987; 46: 329-34.

Haffman SL, Zahidul AA. Preschool child malnutrition in Bangladesh; Causes and intervention. Bangladesh Pediatr. 1983; 7: 98-99.

Hossain M, Kawser CA, Talukder MQ-K. Changing prognosis in severe protein energy malnutrition. Bangladesh Pediatr. 1983; 7: 15-17.

Institute of Public Health Nutrition (IPHN)/Helen Keller International (HKI), Dhaka; Anemia is a severe public health problem in pre-school children and pregnant woman in rural Bangladesh. Nutritional Surveillance Project Bulletin-10. 2002, pp 1-2.

Jelliffe DB, Jelliffe EFP. Community nutrition assessment. Oxford, Oxford University Press, 1989, pp 39-48, 273-351.

Khanum S. Factors contributing to protein energy malnutrition in urban Dhaka. Bangladesh J Child Health. 1985; 9: 80-89.

Koerper MA, Dallman PR. Calif SF. Serum iron concentration and transferrin saturation in the diagnosis of iron deficiency in children: Normal developmental changes. J Pediatr. 1977; 6: 870-74.

Ministry of Health and Family Welfare. Child health situation in Bangladesh: Technical guidelines for child health intervention in Bangladesh. 2003, pp 1-2.

Reddy V, Srikantia SG. Anemia in kwashiorkor. Indian J Med Res. 1970; 58:645-50.

Reeds PJ, Laditan AAO. Serum albumin and transferrin in protein-energy malnutrition. Br J Nutr. 1976; 36: 255-63.

Sarma KVR, Naidu AN. Anemia in children. Indian Pediatr. 1984; 21: 295-98.

Stekel A. Iron nutrition in infancy and childhood. New York, Raven Press, 1984, pp 1-7.

Suskind RM, Suskind LL. The malnourished child. Nestle nutrition workshop series-19. New York, Raven Press, 1990, pp 23-72.

World Health Organization. Management of severe malnutrition. A manual for physicians and other senior health workers. Geneva, World Health Organization, 1999, p 4.

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How to Cite

Rahman, M. A., M. A. Mannan, and M. H. Rahman. “Serum Iron and Total Iron Binding Capacity in Severely Malnourished Children”. Bangladesh Journal of Pharmacology, vol. 2, no. 2, June 2007, pp. 61-65, doi:10.3329/bjp.v2i2.571.



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