Serum osteocalcin and urinary free deoxypyridinoline as potential risk factors in predicting the prevalence of bone trauma among the post-menopausal Chinese women
DOI:
https://doi.org/10.3329/bjp.v13i3.36834Abstract
This study was designed to understand whether the post-menopausal Chinese women (n=175) receiving tablet containing vitamin D (500 IU) and calcium (500 mg) had lower incidence of bone fracture compared to the post-menopausal Chinese women ((n=175) receiving a diet rich in calcium, vitamin D, and protein (milk, cheese, and yogurt, soybeans, spinach, fish including fatty fish, cheese, egg). This study assessed whether the levels of serum osteocalcin and urinary free deoxypyridinoline could be used as predictors of early bone trauma during post-menopausal period. After randomization, subjects were followed-up for up to 3 years to capture required data. The results suggested that therapeutic intervention (vitamin D and calcium) does not predict bone fracture among the post-menopausal Chinese women. However, correlation analysis revealed that the decreased level of serum osteocalcin and urinary free deoxypyridinoline were associated with higher incidence of fracture. The results suggest that the low level of serum osteocalcin and urinary free deoxypyridinoline cause increase susceptibility of fracture among the post-menopausal Chinese women.
Downloads
10
8 Read
1
Additional Files
Published
How to Cite
Issue
Section
License
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
