Is cotoneaster manna improving the treatment of neonatal jaundice?

  • Moloud Fakhri Traditional and Complementary Medicine Research Center, Mazandaran University of Medical Sciences, Sari, Iran. Department of Reproductive Health and Midwifery, Faculty of Nursing and Midwifery, Mazandaran University of Medical Sciences, Sari, Iran. School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran. http://orcid.org/0000-0001-6995-9779
  • Ali Davoodi Department of Pharmacognosy, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran. http://orcid.org/0000-0001-7286-3567
  • Zeinab Hamzegardeshi Traditional and Complementary Medicine Research Center, Mazandaran University of Medical Sciences, Sari, Iran.Department of Reproductive Health and Midwifery, Faculty of Nursing and Midwifery, Mazandaran University of Medical Sciences, Sari, Iran. http://orcid.org/0000-0002-4150-0576
  • Roya Farhadi Department of Pediatrics, Faculty of Medicine, Bouali Hospital, Mazandaran University of Medical Sciences, Sari, Iran.
  • Nouraldin Mousavinasab Department of Biostatistics, Faculty of Health, Mazandaran University of Medical Sciences, Sari, Iran. http://orcid.org/0000-0002-0631-4233
  • Abbasali Keshtkar Department of Health Sciences Education Development, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. http://orcid.org/0000-0002-7305-8639
  • Mohammad Azadbakht Department of Pharmacognosy, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran./Traditional and Complementary Medicine Research Center, Mazandaran University of Medical Sciences, Sari, Iran. http://orcid.org/0000-0002-6298-8718

Abstract

The aim of this systematic review is to evaluate the effects of cotoneaster manna on neonatal jaundice. The studies were selected from 1980 to 2017 using the main databases. Eight clinical trials with a total of 862 infants were selected from the 116 primary studies. All these trials had at least two groups for which the studied outcomes were measured before the intervention and at 12, 24, 36 and 48 hours after intervention. Generally, the meta-regression analysis showed a direct insignificant relationship between the baseline bilirubin level in the infants before the intervention and the estimated results. Although the findings confirm the effectiveness of cotoneaster manna products in the treatment of neonatal jaundice compared to the standard interventions or treatments (phototherapy), further clinical trials are strongly recommended, especially with larger sample sizes, more extensive geogra-phical areas, and a variety of subjects in different parts of the world.

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Author Biography

Mohammad Azadbakht, Department of Pharmacognosy, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran./Traditional and Complementary Medicine Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
Pharmacognosy

References

Ameli Z, Assarroudi A, Akrami R. Effect of bilineaster drop on neonatal hyperbilirubinemia. Evid Base Care. 2017; 6: 66-73.

Azadbakht M, Pishva N, Mohammadi Samani S, Alinejad F. Effect of manna from Cotoneaster discolor on infant jaundice (effect on blood bilirubin level). J Med Plant. 2005; 2: 36-44.

Burke BL, Robbins JM, Mac Bird T, Hobbs CA, Nesmith C, Tilford JM. Trends in hospitalizations for neonatal jaundice and kernicterus in the United States, 1988–2005. Pediatrics 2009; 123: 524-32.

Cohen J. Statistical Power Analysis for the Behavioral Sciences New Jersey Lawrence Erlbaum Associates. Inc. Publishers. 1988

Deeks JJ, Altman DG, Bradburn MJ. Statistical methods for examining heterogeneity and combining results from several studies in meta-analysis. Systematic review health care: Meta-analysis in context. 2001; 2: 285-312.

Duval S, Tweedie R. A nonparametric “trim and fill” method of accounting for publication bias in meta-analysis. J Am Stat Asso. 2000; 95: 89-98.

Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997; 315: 629-34.

Fakhri M, Azadbakht M, Hamze Gardeshi Z, Farhadi R. Purgative manna from Cotoneaster spp. in Iranian traditional medicine and new sources. J Isla Ir Trad Med. 2016; 6: 347-53.

Fakhri M, Azadbakht M, Yousefi SS, Mousavinasab SN, Farhadi R, Azadbakht M. Medicinal plants for treatment of neonatal jaundice by community of Attars (traditional healers) of several urban areas in Mazandaran Province, Northern of Iran. Brit J Med Medica Res. 2016; 14: 1-13.

Fakhri M, Davoodi A, Parviz M, Sadeghi Ghadi Z, Mousavinasab SN, Farhadi R, Azadbakht M, Azadbakht M. Characterization and HPLC analysis of manna from some cotoneaster species. Int J Pharma Sci Res. 2017; 8: 1000-06.

Fallah R, Ali Fallahzadeh M, Noori-Shadkam M. Evaluation of safety and efficacy of purgative manna (billinaster drop) and glycerin suppository in icterus of healthy term newborns. Curr drug saf. 2014; 9: 29-33.

Fok TF. Neonatal jaundice: Traditional Chinese medicine approach. J Perinatol. 2001; 21: S98.

Ghotbi F, Nahidi S, Zangi M. Surveying the effect of Coton-easter spp. (shir khesht) on neonatal jaundice. Res Med. 2006; 30: 353-61.

Group YICSS. Clinical signs that predict severe illness in children under age 2 months: A multicentre study. Lancet 2008; 371: 135-42.

Hedges LV. Estimation of effect size from a series of independent experiments. Psychol Bull. 1982; 92: 490.

Higgins JP, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med. 2002; 21: 1539-58.

Higgins JP, Altman DG, Gotzsche PC, Juni P, Moher D, Oxman AD, Savovic J, Schulz KF, Weeks L, Sterne JA, Cochrane Bias Methods G, Cochrane Statistical Methods G. The Cochrane Collaboration's tool for assessing risk of bias in randomised trials. BMJ. 2011; 343: d5928.

Kassem LM. The efficacy of silymarin in the treatment of physiological neonatal jaundice: A randomized, double-blind, placebo-controlled, clinical trial. J Pediat Sci. 2013; 5: e175

Khodashenas E, Khakshour A, Momeni E, Sinaii M, Mir M. Systemic review of herbal medicine efficacy on neonatal Icterus. J North Khorasan Uni Med Sci. 2016; 7: 683-89.

Kliegman RM, Behrman RE, Jenson HB. Stanton BM. Nelson Textbook of pediatrics e-book, Elsevier Health Sciences, 2007.

Mansouri M, Ghotbi N, Bahadorbeigi L. Evaluation of the preventive effects of purgative manna on neonatal icterus in Sanandaj. Sci J Kurdistan Uni Med Sci. 2012; 17: 30-35.

Moher D, Liberati A, Tetzlaff J, Altman DG, Group P. Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement. PLoS med. 2009; 6: e1000097.

Morris SB, DeShon RP. Combining effect size estimates in meta-analysis with repeated measures and independent-groups designs. Psychol Methods. 2002; 7: 105-25.

Muchowski KE. Evaluation and treatment of neonatal hyperbilirubinemia. Am Fam Physician. 2014; 89: 873-78.

Rafieian-Kopaei M, Khoshdel A, Kheiri S, Shemian R. Cotoneaster: A safe and easy way to reduce neonatal jaundice. J Clin Diagn Res. 2016; 10: Sc01-03.

Reshadmanesh NFK, Kamali Sh. Evaluation of the preventive effects of purgative manna on neonatal icterus in Hazrat Rasul Hospital. Kurdistan Uni Med Sci. 2001; 4: 20-24.

Shah Farhat A, Mohammadzadeh A, Ramezani M, Amiri M. The effect of shirkhesht on newborns’ indirect hyperbilirobinemia. Razi J Med Sci. 2005; 12: 93-98.

Thornton A, Lee P. Publication bias in meta-analysis: Its causes and consequences. J Clin Epidemiol. 2000; 53: 207-16.

Ullah S, Rahman K, Hedayati M. Hyperbilirubinemia in neonates: Types, causes, clinical examinations, preventive measures and treatments: A narrative review article. Iran J Public Health. 2016; 45: 558.

Published
2018-05-31
How to Cite
Fakhri, M., Davoodi, A., Hamzegardeshi, Z., Farhadi, R., Mousavinasab, N., Keshtkar, A., & Azadbakht, M. (2018). Is cotoneaster manna improving the treatment of neonatal jaundice?. Bangladesh Journal of Pharmacology, 13(2), 168-178. https://doi.org/10.3329/bjp.v13i2.36017
Section
Meta-Analysis