Isolation and antifungal screening of endophytic fungi from Erigeron canadensis

  • Xuelian Bai College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 310036
  • Ting Zhou College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 310036
  • Tongfei Lai College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 310036
  • Yicong Li College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 310036
  • Jiale Chai College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 310036
  • Jiajun Ni College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 310036
  • Huawei Zhang School of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014
Keywords: Antifungal, Endophytic fungi, Erigeron canadensis

Abstract

Sixteen fungal strains isolated from the Erigeron canadensis, one of traditional Chinese medicines used to treat the pathogenic infection and dysentery, were evaluated for their antifungal activities against one human pathogen Candida albicans, and two phytopathogens, Colletotrichum fructicola and Rhizoctonia cerealis. The bioassay results indicated that the ethyl acetate extract of the fermentation broth of these fungal endophytes had stronger antimicrobial activities. Among these endophytic strains, the ethyl acetate extracts of strains NPR003 and NPR005 showed the strongest inhibitory effects and has potential application in the discovery of new antifungal agents. This was the first report on the isolation of endophytic fungi from E. canadensis and evaluation of their antifungal activities.

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Author Biography

Huawei Zhang, School of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014
Professor

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Published
2017-07-16
How to Cite
Bai, X., T. Zhou, T. Lai, Y. Li, J. Chai, J. Ni, and H. Zhang. “Isolation and Antifungal Screening of Endophytic Fungi from Erigeron Canadensis”. Bangladesh Journal of Pharmacology, Vol. 12, no. 3, July 2017, pp. 256-9, doi:10.3329/bjp.v12i3.32126.
Section
Research Articles