Mouse model of DNCB-induced atopic dermatitis

Authors

DOI:

https://doi.org/10.3329/bjp.v12i2.31950

Keywords:

Atopic dermatitis, DNCB, Mouse

Abstract

Atopic dermatitis is a skin disease characterized by allergic skin inflammation, redness and itching. The animal model is necessary to find out new drugs. The DNCB-induced animal model of atopic dermatitis includes the following steps: 1) Selection of animals; 2) Shaving of dorsal skin; 3) Applying DNCB once in 24 hours for three days; 4) Monitoring the development of atopy on day 4 post DNCB application. Further, the efficacy of reference drug can be determined by applying on the atopy skin, depends on the nature and aim of the work.

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Author Biographies

Alshammari Fanar Hamad, Department of Applied Microbiology and Biotechnology, School of Biotechnology, Yeungnam University, Gyeongsan, Gyeongbuk 712749

Phone: +82-53-810-3842; Fax: +82-53-813-4620; Mobile: +82-(0)10-4274-4744 

Jong-Hun Han, Department of Applied Microbiology and Biotechnology, School of Biotechnology, Yeungnam University, Gyeongsan, Gyeongbuk 712-749

Miobile: +82-(0)010-2558-2636

Irfan Ahmad Rather, Department of Applied Microbiology and Biotechnology, School of Biotechnology, Yeungnam University, Gyeongsan, Gyeongbuk 712-749

Assistant Professor

References

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Published

2017-04-30

How to Cite

Hamad, A. F., J.-H. Han, and I. A. Rather. “Mouse Model of DNCB-Induced Atopic Dermatitis”. Bangladesh Journal of Pharmacology, vol. 12, no. 2, Apr. 2017, p. Available Online: Apr 30, 2017, doi:10.3329/bjp.v12i2.31950.

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Section

Visual Experiment