Evaluation of pharmacological effect of Teucrium stocksianum extract on angiogenesis using chorioallantoic membrane assay

  • Nazia Tabassum Department of Pharmacy, University of Sargodha, Sargodha
  • Alamgeer . Department of Pharmacy, University of Sargodha, Sargodha
  • Abdul Aziz Department of Pharmacy, Bahauddin Zakariya University, Multan http://orcid.org/0000-0001-5393-3806
  • Bashir Ahmad University College of Pharmacy, University of the Punjab, Lahore
Keywords: Anti-angiogenesis, CAM assay, Teucrium stocksianum

Abstract

The present study was aimed to evaluate the effect of Teucrium stocksianum on angiogenesis by using chorioallantoic membrane (CAM) assay. Fertilized eggs were incubated on the 5th day and dose of different dilutions 0.03%, 0.05%, 0.1%, and 0.5% of the plant extract was applied on 6th day. Evaluation of primary, secondary and tertiary blood vessels diameter and CAM area on 7th day by SPIP software. T. stocksianum showed antiangiogenic effect by reducing the diameter of CAM of blood vessels by applying the dilutions while significant results were obtained at dilution of 0.5%.

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Author Biographies

Nazia Tabassum, Department of Pharmacy, University of Sargodha, Sargodha
Lecturer
Abdul Aziz, Department of Pharmacy, Bahauddin Zakariya University, Multan
Lecturer
Bashir Ahmad, University College of Pharmacy, University of the Punjab, Lahore
Principal

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Published
2016-06-14
How to Cite
Tabassum, N., A. ., A. Aziz, and B. Ahmad. “Evaluation of Pharmacological Effect of Teucrium Stocksianum Extract on Angiogenesis Using Chorioallantoic Membrane Assay”. Bangladesh Journal of Pharmacology, Vol. 11, no. 3, June 2016, pp. 621-7, doi:10.3329/bjp.v11i3.24472.
Section
Research Articles