Anti-oxidant and hepatoprotective activities of total flavonoids of Indocalamus latifolius

Authors

  • Juan Tan The Department of Life Science, Huaihua University, Huaihua 418008
  • Li Shenghua The Department of Life Science, Huaihua University, Huaihua 418008 http://orcid.org/0000-0002-0042-1855
  • Junying Zeng The Department of Life Science, Huaihua University, Huaihua 418008
  • Xianjin Wu The Department of Life Science, Huaihua University, Huaihua 418008

DOI:

https://doi.org/10.3329/bjp.v10i4.23496

Keywords:

Anti-oxidant, Flavonoid, Hepatoprotective, Indocalamus latifolius

Abstract

The total flavonoids of Indocalamus latifolius were evaluated in term of their anti-oxidant and hepatoprotective activities. The results showed that in vitrohepatoprotective and anti-oxidant activities of total flavonoids at doses of 200 and 400 mg/kg and 100 mg/kg, respectively, were comparable to those of the known hepatoprotective drug silymarin at 100 mg/kg. These data were supplemented with histopathological studies of rat liver sections. Seven of the main flavonoid compounds purified by column chromatography using silica gel, sephadex LH-20 and develosil ODS, and determined to be vitexin, orientin, isovitexin, homoorientin, tricin, tricin-7-O-β-D-glucopyranoside and quercetin-3-O-glucopyranoside.

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Published

2015-09-26

How to Cite

Tan, J., L. Shenghua, J. Zeng, and X. Wu. “Anti-Oxidant and Hepatoprotective Activities of Total Flavonoids of Indocalamus Latifolius”. Bangladesh Journal of Pharmacology, vol. 10, no. 4, Sept. 2015, pp. 779-8, doi:10.3329/bjp.v10i4.23496.

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Section

Research Articles