Anticancer and apoptosis-inducing effects of Moringa concanensis using hepG2 cell lines

Authors

  • V. Balamurugan Research and Development Centre, Bharathiar University, Coimbatore 641 046, Tamil Nadu
  • Veluchamy Balakrishnan Research and Development Centre, Bharathiar University, Coimbatore 641 046, Tamil Nadu
  • J. Philip Robinson Department of Biotechnology, K. S. Rangasamy College of Technology (Autonomous), Tiruchengode 637 215, Tamil Nadu
  • M. Ramakrishnan Department of Biotechnology, Sri Vinayaga College of Arts and Science, Ulundurpet 606 107, Tamil Nadu

DOI:

https://doi.org/10.3329/bjp.v9i4.20481

Keywords:

Anti-cancer, HepG-2 cell line, Moringa concanensis, MTT assay

Abstract

The objective of the present investigation is focused on the anticancer activity of the ethanolic crude extract of Moringa concanensis leaf and bark against HepG2 cell line. The study was facilitated by collecting the plant sample and subjected to ethanol crude extraction. The anticancer activity of the crude extracted sample against HepG2 cell line was examined by MTT assay. The study confirms that the leaf crude extract of M. concanensis has pronounced anticancer potential against HepG2 cell lines while compared to that of the bark extract. The plant investigated possesses remarkable anticancer activity and hence isolation of the compound contributing to the activity may lead to develop at a novel and natural phytomedicine for the disease.

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Author Biography

Veluchamy Balakrishnan, Research and Development Centre, Bharathiar University, Coimbatore 641 046, Tamil Nadu

Associate Professor

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Published

2014-11-20

How to Cite

Balamurugan, V., V. Balakrishnan, J. P. Robinson, and M. Ramakrishnan. “Anticancer and Apoptosis-Inducing Effects of Moringa Concanensis Using HepG2 Cell Lines”. Bangladesh Journal of Pharmacology, vol. 9, no. 4, Nov. 2014, pp. 604-9, doi:10.3329/bjp.v9i4.20481.

Issue

Section

Research Articles