Hypoglycemic activity of aqueous leaf extract of Limonia elephantum in alloxan-induced diabetic rats

  • K. Kamalakannan Department of Biotechnology, Nandha College of Pharmacy, Erode 638 052, Tamil Nadu
  • Veluchamy Balakrishnan Department of Biotechnology, K. S. Rangasamy College of Technology, Tiruchengode 637 215, Tamil Nadu
Keywords: Alloxan, Antidiabetic, Glucose tolerance test, Hypoglycemic, Limonia elephantuma

Abstract

The hypoglycemic activity of the aqueous leaf extract of Limonia elephantum was evaluated. The extract was administered orally 1,000 mg/kg to normal and alloxan-induced (55 mg/kg body weight, i.v) diabetic rats. The hypoglycemic effect of the extract was statistically significant with an oral dose of 1,000 mg/kg and was comparable to that of the effect produced by standard antidiabetic agent, metformin 1.5 mg/kg. The extract increased the glucose tolerance using oral glucose tolerance test.

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Author Biography

Veluchamy Balakrishnan, Department of Biotechnology, K. S. Rangasamy College of Technology, Tiruchengode 637 215, Tamil Nadu
Associate Professor

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Published
2014-09-17
How to Cite
Kamalakannan, K., and V. Balakrishnan. “Hypoglycemic Activity of Aqueous Leaf Extract of Limonia Elephantum in Alloxan-Induced Diabetic Rats”. Bangladesh Journal of Pharmacology, Vol. 9, no. 3, Sept. 2014, pp. 443-6, doi:10.3329/bjp.v9i3.19705.
Section
Research Articles