Growth inhibitory effect of ethanolic neem leaves extract on Klebsiella, Salmonella and Staphylococcus aureus

  • Quazi Rubyath Banna Department of Pharmacology and Therapeutics, Sir Salimullah Medical College, Dhaka
  • Feroza Parveen Department of Pharmacology and Therapeutics, Sir Salimullah Medical College, Dhaka
  • Md. Jalaluddin Iqbal Department of Pharmacology and Therapeutics, Sir Salimullah Medical College, Dhaka
Keywords: Azadirachta indica, Klebsiella, Salmonella, Staphylococcus aureus, Minimum inhibitory concentration (MIC)

Abstract

Neem (leaves, flowers, seeds etc.) have been used traditionally against many diseases. We, thus, investigated the antimicrobial effect of ethanolic neem leave extract on Klebsiella, Salmonella and Staphylococcus aureus and found its growth inhibitory effect on Klebsiella and Salmonella at the concentration of 12.5 mg/mL and 6.2 mg/mL respectively with average diameter of zone of inhibition 18 mm and 20 mm respectively. It failed to inhibit the growth of Staphylococcus aureus at the highest concentration used (50 mg/mL). Findings of this preliminary experimental study suggest that, neem can be tried against Klebsiella and Salmonella showing limited efficacy.

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Author Biographies

Feroza Parveen, Department of Pharmacology and Therapeutics, Sir Salimullah Medical College, Dhaka
Professor
Md. Jalaluddin Iqbal, Department of Pharmacology and Therapeutics, Sir Salimullah Medical College, Dhaka
Associate Professor

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Published
2014-08-05
How to Cite
Banna, Q., F. Parveen, and M. Iqbal. “Growth Inhibitory Effect of Ethanolic Neem Leaves Extract on Klebsiella, Salmonella and Staphylococcus Aureus”. Bangladesh Journal of Pharmacology, Vol. 9, no. 3, Aug. 2014, pp. 347-50, doi:10.3329/bjp.v9i3.19454.
Section
Research Articles