Antihyperglycemic activity of Trichosanthes tricuspidata root extract

  • Srinivasan Kulandaivel Natural Products Research Laboratory, Department of Pharmaceutical Chemistry, Nandha College of Pharmacy, Erode 638052, Tamil Nadu
  • Pawan Bajpai Natural Products Research Laboratory, Department of Pharmaceutical Chemistry, Nandha College of Pharmacy, Erode 638052, Tamil Nadu
  • Thangavel Sivakumar Natural Products Research Laboratory, Department of Pharmaceutical Chemistry, Nandha College of Pharmacy, Erode 638052, Tamil Nadu
Keywords: Alloxan, Anti-hyperglycemic activity, Trichosanthes tricuspidata


To evaluate the anti-diabetic activity of ethanolic extract of Trichosanthes tricuspidata root in alloxan induced diabetic rats and to perform the phytochemical screening. The extraction, preliminary phytochemical screening, anti-diabetic activity in alloxan induced diabetic rats  by oral administration of  extract (200 and 400 mg/kg b.w.), the blood glucose level and biochemical parameters like cholesterol, triglyceride, serum protein, SGPT, SGOT, and ALP were estimated. Phytochemical studies shows the presence of carbohy-drates, proteins, glycosides and terpenoids and the ethanolic extract of T. tricuspidata root significantly lowered the blood sugar level. The above findings justified the traditional claim of anti-diabetic activity in this plant.


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How to Cite
Kulandaivel, S., P. Bajpai, and T. Sivakumar. “Antihyperglycemic Activity of Trichosanthes Tricuspidata Root Extract”. Bangladesh Journal of Pharmacology, Vol. 8, no. 3, July 2013, pp. 305-10, doi:10.3329/bjp.v8i3.15584.
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