Potential anti-diabetic activity of Bombax ceiba

Chetan Bhavsar, Gokul S. Talele


Bombax ceiba bark extract was evaluated for its hypoglycemic and hypolipide-mic potential through normal and streptozotocin-induced diabetic rats administered with graded oral doses (200, 400, 600 mg/kg/day) for 21 days. The results showed that a dose of 600 mg/kg of B. ceiba extract is the most effective to cause significant (p<0.001) hypoglycemic and/or hypolipidemic effects on  streptozotocin-induced diabetic rats. This dose also significant-ly (p<0.001) lowered the total cholesterol and triglyceride level in severely diabetic rats. Phytochemical and GC-MS studies confirmed the presence of the triterpenoid compounds in the extract, which may account for its significant hypoglycemic activity. The present study thus provides a scientific rationale for the traditional use of this plant in the management diabetes.




Kantesavar, Toranmal, Hypoglycemic, Hypolipidemic, Streptozotocin

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DOI: http://dx.doi.org/10.3329/bjp.v8i2.13701

Copyright (c) 2013 Chetan Bhavsar, Gokul S. Talele

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