Potential anti-diabetic activity of Bombax ceiba

  • Chetan Bhavsar R.C. Patel Institute of Pharmaceutical Education and Research, Shirpur, Dhule
  • Gokul S. Talele NGSPM?s College of Pharmacy, Brahma Valley Educational campus, Trimbak road, Anjaneri, Nashik
Keywords: Kantesavar, Toranmal, Hypoglycemic, Hypolipidemic, Streptozotocin

Abstract

Bombax ceiba bark extract was evaluated for its hypoglycemic and hypolipide-mic potential through normal and streptozotocin-induced diabetic rats administered with graded oral doses (200, 400, 600 mg/kg/day) for 21 days. The results showed that a dose of 600 mg/kg of B. ceiba extract is the most effective to cause significant (p<0.001) hypoglycemic and/or hypolipidemic effects on  streptozotocin-induced diabetic rats. This dose also significantly (p<0.001) lowered the total cholesterol and triglyceride level in severely diabetic rats. Phytochemical and GC-MS studies confirmed the presence of the triterpenoid compounds in the extract, which may account for its significant hypoglycemic activity. The present study thus provides a scientific rationale for the traditional use of this plant in the management diabetes.

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Published
2013-02-26
How to Cite
Bhavsar, C., and G. Talele. “Potential Anti-Diabetic Activity of Bombax Ceiba”. Bangladesh Journal of Pharmacology, Vol. 8, no. 2, Feb. 2013, pp. 102-6, doi:10.3329/bjp.v8i2.13701.
Section
Research Articles