In vitro glucose uptake by isolated rat hemidiaphragm study of Aegle marmelos Correa root
Keywords:Aegle marmelos, Anti-diabetic, 6-Methyl-4-chromanone, Skimmianine
The methanol extract of the root of Aegle marmelos, a medicinal plant, was fractionated into eight fractions using column chromatography. The anti-diabetic activity of all the fractions was studied using the glucose uptake by isolated rat hemidiaphragm in vitro model. Using the bioassay-guided fractionation, two compounds 1 and 2 were isolated by column chromatography and identified as 6-methyl-4-chromanone and skimmianine respectively by NMR and mass spectral methods.
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