In vitro glucose uptake by isolated rat hemidiaphragm study of Aegle marmelos Correa root

  • Subban Ravi Department of Chemistry, Karpagam University, Coimbatore, Tamilnadu
  • C. T. Sadashiva Phytochemistry Division, Centre for Medicinal Plants Research, Arya Vaidya Sala, Kottakkal 676503, Kerala
  • T. Tamizmani Bharathi college of Pharmacy, Bharathi Nagara, Mandya, Karnataka 571422
  • T. Balasubramanian Bharathi college of Pharmacy, Bharathi Nagara, Mandya, Karnataka 571422
  • M. Rupeshkumar Bharathi college of Pharmacy, Bharathi Nagara, Mandya, Karnataka 571422
  • Indira Balachandran Phytochemistry Division, Centre for Medicinal Plants Research, Arya Vaidya Sala, Kottakkal 676503, Kerala
Keywords: Aegle marmelos, Anti-diabetic, 6-Methyl-4-chromanone, Skimmianine

Abstract

The methanol extract of the root of Aegle marmelos, a medicinal plant, was fractionated into eight fractions using column chromatography. The anti-diabetic activity of all the fractions was studied using the glucose uptake by isolated rat hemidiaphragm in vitro model. Using the bioassay-guided fractionation, two compounds 1 and 2 were isolated by column chromatography and identified as 6-methyl-4-chromanone and skimmianine respectively by NMR and mass spectral methods.

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Author Biography

Subban Ravi, Department of Chemistry, Karpagam University, Coimbatore, Tamilnadu

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References

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Published
2008-11-05
How to Cite
Ravi, S., C. T. Sadashiva, T. Tamizmani, T. Balasubramanian, M. Rupeshkumar, and I. Balachandran. “In Vitro Glucose Uptake by Isolated Rat Hemidiaphragm Study of Aegle Marmelos Correa Root”. Bangladesh Journal of Pharmacology, Vol. 4, no. 1, Nov. 2008, pp. 65-68, doi:10.3329/bjp.v4i1.1211.
Section
Research Articles