Glycated haemoglobin acts as an indicator of dislipidemia in patients with Type II diabetes mellitus

Authors

  • Sumaia Sahrin Department of Human Nutrition and Dietetics, Patuakhali Science and Technology University, Dumki, Patuakhali-8602
  • Dilruba Easmin Jharna Department of Human Nutrition and Dietetics, Patuakhali Science and Technology University, Dumki, Patuakhali-8602
  • M Shafiqul Islam Khan Department of Food Microbiology, Patuakhali Science and Technology University, Dumki, Patuakhali-8602
  • Jayati Debnath Department of Human Nutrition and Dietetics, Patuakhali Science and Technology University, Dumki, Patuakhali-8602
  • Suman Talukder Department of Community Health and Hygiene, Patuakhali Science and Technology University, Dumki, Patuakhali-8602

DOI:

https://doi.org/10.3329/ralf.v5i2.38104

Keywords:

Glycemic control, HbA1c, Serum lipid profile, Type 2 diabetes

Abstract

Diabetic patients with associated dyslipidemia are easy targets for cardiovascular diseases (CVD). Glycated hemoglobin predicts the risk for the development of diabetic complications. This study was an attempt to determine lipid abnormalities associated with Type-2 Diabetes Mellitus and association between glycated hemoglobin (HbA1c) levels and serum lipid profile to assess the importance of HbA1c as an indicator of dyslipidemia and future risk of cardiovascular disease in Bhola District, Barisal. In this cross-sectional study, 200 known patients of Type-2 Diabetes Mellitus within 35-85 years of age were randomly selected. They were investigated for HbA1c and lipid profile. The data were evaluated by Statistical Package for Social Sciences (SPSS) 16.0 version software. Independent samples t-test (2-tailed) was used to compare means of anthropometric, clinical and laboratory parameters and the effect of the glycemic control on their lipid profile was determined using correlation coefficient. Amongst the study group, 65% patients showed poor glycemic control, 35% with good glycemic control and 59.60% patient’s haddyslipidemia.HbA1c was found to have significant positive correlation with total cholesterol (TCHO), low density lipoprotein (LDL-C) and triglycerides (TG) and significant negative correlation with high density lipoprotein (HDL-C). The mean value of TC, LDL-C and TG was found to be lower in patients with good glycemic control than those with poor glycemic control. These differences were significant at the level of P<0.05. These findings conclude that the glycemic control of the patient has got a strong impact on the serum lipid level and dyslipidemia is frequently encountered in those who have got poor glycemic control.

Res. Agric., Livest. Fish.5(2): 185-192, August 2018

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Published

2018-09-09

How to Cite

Sahrin, S., Jharna, D. E., Khan, M. S. I., Debnath, J., & Talukder, S. (2018). Glycated haemoglobin acts as an indicator of dislipidemia in patients with Type II diabetes mellitus. Research in Agriculture Livestock and Fisheries, 5(2), 185–192. https://doi.org/10.3329/ralf.v5i2.38104

Issue

Vol. 5 No. 2 (2018)

Section

Livestock

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