Clinical Presentation and Associated Risk Factors of Adult Pulmonary Tuberculosis Cases in Dhaka, Bangladesh

Authors

  • Md Zaber Assistant Professor, Department of Microbiology, Gazi Medical College, Khulna, Bangladesh. https://orcid.org/0009-0000-5572-2471
  • Md Sohanur Rahman Assistant Professor, Department of Community Medicine, Army Medical College, Jashore, Bangladesh.
  • Nur Mohammad Khan Associate Professor (c.c), Department of Microbiology, Ad-din Momin Medical College, Dhaka, Bangladesh.
  • Tasnim Rahman Associate Professor, Department of Pathology. Gazi Medical College, Khulna, Bangladesh.
  • Abu Md Mayeenuddin Al Amin Associate Professor, Department of Microbiology, Gazi Medical College, Khulna, Bangladesh.

DOI:

https://doi.org/10.3329/mediscope.v13i1.87101

Keywords:

Tuberculosis, Bangladesh, Clinical features, Risk factors, Smoking, Demographic profile

Abstract

Background: Tuberculosis (TB) remains one of the leading causes of death worldwide, particularly in developing countries like Bangladesh. Understanding the demographic distribution, clinical features, and associated risk factors among TB patients is essential for improving case detection and control strategies.

Objective: This study aimed to assess the sociodemographic characteristics, clinical manifestations, and risk factors among diagnosed cases of pulmonary tuberculosis.

Methods: A descriptive cross-sectional study was conducted from March 2022 to February 2023 at the Department of Microbiology & Immunology, Bangabandhu Sheikh Mujib Medical University (BSMMU), and the National Tuberculosis Reference Laboratory, Dhaka, Bangladesh. Seventy-four confirmed pulmonary TB patients aged ≥18 years were enrolled based on real-time PCR positivity for Mycobacterium tuberculosis. Data were collected using a predesigned questionnaire and analyzed descriptively.

Results: The majority of the cases (37.8%) were aged 18–30 years, followed by 31–40 years (32.4%), with a marked male predominance (71.6%). Businessmen (24.3%) and students (20.3%) were the most affected occupational groups. The predominant clinical features included cough lasting more than two weeks (83.8%), respiratory distress (73.0%), and fever persisting for more than two weeks (54.1%). Weight loss, hemoptysis, and anemia were observed in 23.0%, 20.3%, and 14.9% of cases, respectively. Smoking was the most common risk factor (54.1%), followed by chronic respiratory diseases (16.2%) and family history of TB (10.8%).

Conclusion: Pulmonary tuberculosis predominantly affects young, economically productive males in Bangladesh, with smoking emerging as a major associated risk factor. The high frequency of advanced symptoms at presentation highlights delayed diagnosis and health-seeking behavior. Strengthening early case detection, integrating smoking cessation programs, and enhancing community awareness are crucial to reducing TB transmission and improving outcomes.

Mediscope 2026;13(1): 52-57

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Published

2026-02-01

How to Cite

Zaber, M., Rahman, M. S., Nur Mohammad Khan, Tasnim Rahman, & Amin, A. M. M. A. (2026). Clinical Presentation and Associated Risk Factors of Adult Pulmonary Tuberculosis Cases in Dhaka, Bangladesh. Mediscope, 13(1), 52–57. https://doi.org/10.3329/mediscope.v13i1.87101

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Section

Original Articles