Disseminated histoplasmosis in a renal transplant recipient – a fatal case report

Authors

  • Tânia Mara L.B. Araújo Hospital São José de Doenças Infecciosas, Secretaria da Saúde do Estado do Ceará. Fortaleza, Ceará
  • Geraldo B. Silva Junior Department of Internal Medicine, School of Medicine, Federal University of Ceara. Fortaleza, Cearal and School of Medicine, Health Sciences Center, University of Fortaleza. Fortaleza, Ceará
  • Orivaldo A. Barbosa Departament of Internal Medicine, Federal University of Ceará. Fortaleza, Ceará
  • Rafael S.A. Lima Departament of Internal Medicine, University of São Paulo. Ribeirão Preto, São Paulo, Brazil
  • Elizabeth F. Daher Departament of Internal Medicine, Federal University of Ceará. Fortaleza, Ceará, Brazil

DOI:

https://doi.org/10.3329/jom.v12i2.7125

Keywords:

Disseminated histoplasmosis, Kidney transplantation, Immunosuppression

Abstract

Histoplasmosis is an infectious disease caused by the dimorphic fungus Histoplasma capsulatum.. The disseminated form is usually found in immunocompromised patients. A 53 year-old man, renal transplant recipient, was admitted with fever, dyspnea, productive cough, adynamia and weight loss. He was septic, but hemodynamically stable. The tracheal aspirate found intracellular fungi and the peripheral blood exam was compatible with histoplasmosis. The patient presented a progressive worsening of respiratory pattern and needed mechanical ventilation, vasoactive drugs and hemodialysis. A large spectrum antimicrobial therapy was started, including amphotericin B, but the patient died.

Keyword: Disseminated histoplasmosis. Kidney transplantation. Immunosuppression

DOI: http://dx.doi.org/10.3329/jom.v12i2.7125

JOM 2011; 12(2): 163-165

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Published

2011-08-22

How to Cite

Araújo, T. M. L., Silva Junior, G. B., Barbosa, O. A., Lima, R. S., & Daher, E. F. (2011). Disseminated histoplasmosis in a renal transplant recipient – a fatal case report. Journal of Medicine, 12(2), 163–165. https://doi.org/10.3329/jom.v12i2.7125

Issue

Section

Case Reports