Pattern of Hematological Manifestations in Patients with Systemic Lupus Erythematosus Attending in a Tertiary Care Hospita
Keywords:Systemic Lupus Erythematosus, hematological manifestations, anemia, leucopenia, thrombocytopenia.
Background: Hematological manifestations are not uncommon with systemic lupus erythematosus (SLE). Some of them are life-threatening, warranting prompt action, while others need special consideration. This study aimed at pattern of hematological manifestations in patients with SLE.
Materials and Methods: This descriptive cross sectional study included patients who were diagnosed and treated as SLE at Dhaka Medical College Hospital. Detailed history and physical examinations were performed in every patient. SLE was diagnosed as per ACR criteria. Necessary investigations were carried out. Hematological manifestations were scrutinized and statistically analyzed.
Results: A total of 89 patients (97.8% females, mean age 24.86 ±5.88 years) were studied. Hematological manifestations were present in 77 (85.4%) patients at the time of diagnosis. Among them anemia was most frequent in 77.5% patients followed by neutropenia (19.1%), lymphopenia (17.9%), thrombocytopenia (17.9%), autoimmune hemolytic anemia (AIHA) in 10.1% and pancytopenia in 5.6% patients. Normocytic normochromic anemia (NNA) was the most common peripheral blood film (PBF) findings found in 31 (34.8%) of the patient, followed by microcytic hypochromic anemia (MHA) (32.6%).
Conclusion: Hematological manifestations are frequently encountered in SLE. A sound conception about the relative frequency of hematological manifestations associated with systemic lupus erythematosus will help the clinician to take necessary measures for the wellbeing of the patient.
J MEDICINE July 2017; 18 (2) : 86-91
How to Cite
LicenseAuthors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).