Seropositive Neuromyelitis Optica (Devic’s Disease): A Rare Case Report

Authors

  • Md Golam Ur Rahaman Indoor Medical Officer, Department of Medicine, Dhaka Medical College & Hospital, Dhaka
  • Azizul Haque Indoor Medical Officer, Department of Medicine, Dhaka Medical College & Hospital, Dhaka
  • Shuvra Adhikary Medical Officer, Department of Medicine, Dhaka Medical College & Hospital, Dhaka
  • Chowdhury Tamanna Tabassum Medical Officer, Department of Medicine, Dhaka Medical College & Hospital, Dhaka
  • Ahmedul Kabir Associate Professor, Department of Medicine, Dhaka Medical College & Hospital, Dhaka
  • Sudip Ranjan Deb Assistant professor, Department of Medicine, Dhaka Medical College & Hospital, Dhaka

DOI:

https://doi.org/10.3329/jom.v17i2.30079

Keywords:

Neuromyelitis optica, Devic’s disease, Immunoglobulin G (IgG), aquaporin-4 (AQP4)

Abstract

Neuromyelitis optica or Devics disease is a rare inflammatory demyelinating autoimmune disease of the central nervous system which affects the spinal cord and optic nerves and usually associated with increased disability and morbidity. The purpose of this case report is to present this rare disease and focus on diagnostic criteria. NMO is often misdiagnosed as Multiple Sclerosis. The discovery of neuromyelitis optica (NMO) immunoglobulin G (IgG), directed against aquaporin-4 (AQP4), has dramatically changed the clinical definition of NMO and is important in the diagnostic criteria of this disease. Also longitudinally extensive spinal cord lesions (3 or more spinal segments) are characteristic of NMO. Here we report a case of a 14 year old girl presented with weakness of all four limbs with left sided complete blindness. NMO was diagnosed because of characteristic MRI finding and positive Aquaporin 4 IgG positive.

J MEDICINE July 2016; 17 (2) : 122-124

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Author Biography

Md Golam Ur Rahaman, Indoor Medical Officer, Department of Medicine, Dhaka Medical College & Hospital, Dhaka



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Published

2016-10-23

How to Cite

Rahaman, M. G. U., Haque, A., Adhikary, S., Tabassum, C. T., Kabir, A., & Deb, S. R. (2016). Seropositive Neuromyelitis Optica (Devic’s Disease): A Rare Case Report. Journal of Medicine, 17(2), 122–124. https://doi.org/10.3329/jom.v17i2.30079

Issue

Section

Case Reports