Multicentric Hyaline-Vascular Castleman Disease: A Case Report

Authors

  • Aparna Das Assoc. Prof., Dept.of Medicine, Dhaka Medical College & Hospital, Dhaka
  • Sanjana Tarannum HMO, Dept.of Medicine, Dhaka Medical College & Hospital, Dhaka
  • Tahera Kona HMO, Dept.of Medicine, Dhaka Medical College & Hospital, Dhaka
  • Santanu Kumar Saha IMO, Dept.of Medicine, Dhaka Medical College & Hospital, Dhaka
  • MA Kahhar Professor, Dept. of Medicine, Dhaka Medical College & Hospital

DOI:

https://doi.org/10.3329/jom.v16i1.22402

Keywords:

Lymphadenopathy, lymphoma, Castleman disease

Abstract

Castleman disease is a rare lymphoproliferative disorder. Contrary to its closest differential of lymphoma, the disease tends to run a benign course. However the multicentric variety, which is usually of the plasma cell type, has a more sinister prognosis. It is commonly associated with HIV infection. We report a case of a 65 year old man presenting with recurrent episodes of swelling of the whole body and diarrhoea for 3 years. Physical examination revealed generalized lymphadenopathy with hepato-splenomegaly and ascites. Lymph node biopsy revealed histopathological changes consistent with hyaline-vascular type of Castleman disease (multicentric). He was HIV negative. Patient was treated with high dose corticosteroids and discharged with follow up advice.

DOI: http://dx.doi.org/10.3329/jom.v16i1.22402

J MEDICINE 2015; 16 : 48-50

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Published

2015-02-25

How to Cite

Das, A., Tarannum, S., Kona, T., Saha, S. K., & Kahhar, M. (2015). Multicentric Hyaline-Vascular Castleman Disease: A Case Report. Journal of Medicine, 16(1), 48–50. https://doi.org/10.3329/jom.v16i1.22402

Issue

Section

Case Reports