Cold Agglutinin Disease Secondary to Multiple Myeloma in a Psoriatic Patient

Authors

  • Hazera Khatun Square Hospital, Dhaka
  • Salma Afrose Dhaka Medical College & Hospital, Dhaka
  • Mohiuddin Ahmed Khan Dhaka Medical College & Hospital, Dhaka
  • Tasneem Ara Dhaka Medical College & Hospital, Dhaka
  • Md. Sirajul Islam Sir Salimullah Medical College & Hospital, Dhaka

DOI:

https://doi.org/10.3329/jom.v15i2.20688

Keywords:

Cold agglutinin disease, multiple myeloma, psoriasis

Abstract

Cold agglutinin disease (CAD) is a chronic compensated hemolytic anemia. We report a case of cold agglutinin disease secondary to multiple myeloma (MM) in a patient of erythrodermic psoriasis. The patient presented with acral cyanosis, progressive weakness and generalized desquamating scaly lesions. After confirming the diagnosis (80-90% plasma cells in bone marrow, M- spike in serum protein electrophoresis, G-ë restriction pattern in immune electrophoresis) he was given chemotherapy with CTD (cyclophosphamide, thalidomide and dexamethasone) protocol. His clinical symptoms improved and he has now completed 4 cycles of chemotherapy. The interim follow up showed achievement of PR (partial response).

DOI: http://dx.doi.org/10.3329/jom.v15i2.20688

J MEDICINE 2014; 15 : 141-143

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Author Biographies

Hazera Khatun, Square Hospital, Dhaka

Specialist in Haematology

Salma Afrose, Dhaka Medical College & Hospital, Dhaka

Associate Professor, Department of Haematology

Mohiuddin Ahmed Khan, Dhaka Medical College & Hospital, Dhaka

Professor & Head of the department, Department of
Haematology

Tasneem Ara, Dhaka Medical College & Hospital, Dhaka

Assistant Professor, Department of Haematology

Md. Sirajul Islam, Sir Salimullah Medical College & Hospital, Dhaka

Assistant Professor, Department of Haematology

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Published

2014-10-19

How to Cite

Khatun, H., Afrose, S., Khan, M. A., Ara, T., & Islam, M. S. (2014). Cold Agglutinin Disease Secondary to Multiple Myeloma in a Psoriatic Patient. Journal of Medicine, 15(2), 141–143. https://doi.org/10.3329/jom.v15i2.20688

Issue

Section

Case Reports