Estimation of Serum Ferritin - A Better Screening Test for Blood Donors
Keywords:Blood donors, blood donation, iron deficiency, haemogram, serum ferritin
Background: Haemoglobin and haematocrit estimation are the commonest methods used worldwide in Blood Banks to screen donors. In order to detect Non-anaemic iron deficient state in repeat donors, these tests are inadequate. Several studies have reported a high incidence of iron deficiency in repeat donors.
Aims: The present study was undertaken to assess routine haematological parameters and body iron stores of blood donors in order to identify those who were potentially prone to develop iron deficiency anaemia.
Method: Predonation haemoglobin, haemogram and serum ferritin were done in 116 male donors. These were divided into two groups on the basis of number of donations.
Results: First time donors (81.07±97.12) had higher mean serum ferritin level than those in repeat donors (46.01±49.09). 10.52% of first time donors and 27.5% of repeat blood donors were found to be iron deficient as indicated by serum ferritin level <12 ng/ml. In addition a higher RBC count, reticulocyte % and lower MCV were noted in repeat donors.
Conclusion: We concluded that haemoglobin estimation was not adequate to detect iron deficient non anaemic state in repeat blood donors. Serum ferritin proved to be a better investigation to detect the same and should be done in repeat donors. Iron supplementation for an adequate period post donation is recommended.
J Medicine 2012; 13 : 174-178
How to Cite
LicenseAuthors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).