Synthesis And Characterization Of Methyl 4, 6-O-Enzylidene- ?-D-Glucopyranoside Derivatives

Authors

  • Sarkar MA Kawsar Laboratory of Carbohydrate and Protein Chemistry, Department of Chemistry, Faculty of Science, University of Chittagong, Chittagong-4331
  • Abul KMS Kabir Laboratory of Carbohydrate and Protein Chemistry, Department of Chemistry, Faculty of Science, University of Chittagong, Chittagong-4331
  • MOhammad MR Bhuiyan Department of Chemistry, School of Science and Technology, University of New England, Armidale NSW 2351
  • Mohammad M Manik Laboratory of Carbohydrate and Protein Chemistry, Department of Chemistry, Faculty of Science, University of Chittagong, Chittagong-4331

DOI:

https://doi.org/10.3329/jbcs.v25i2.15045

Abstract

Regioselective benzoylation of methyl 4,6-O-benzylidene-?-D-glucopyranoside (1) using direct acylation method furnished the methyl 4,6-O-benzylidene-2-O-(4-t-butylbenzoyl)- ?-D-glucopyranoside (2) in an excellent yield. In order to obtain newer products for antimicrobial screening studies, the 2-O-4-t-butylbenzoyl derivative was further transformed to a series of 3-O-acyl derivatives (2-12) containing a wide variety of functionalities in a single molecular framework.

Journal of Bangladesh Chemical Society, Vol. 25(2), 101-109, 2012

DOI: http://dx.doi.org/10.3329/jbcs.v25i2.15045

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Published

2013-05-21

How to Cite

Kawsar, S. M., Kabir, A. K., Bhuiyan, M. M., & Manik, M. M. (2013). Synthesis And Characterization Of Methyl 4, 6-O-Enzylidene- ?-D-Glucopyranoside Derivatives. Journal of the Bangladesh Chemical Society, 25(2), 101–109. https://doi.org/10.3329/jbcs.v25i2.15045

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