Microemulsions as Nanoreactors for Preparation of Nanoparticles with Antibacterial Activity

  • Sakhawat Hossain Department of Chemistry, University of Dhaka, Dhaka-1000
  • Ummul K Fatema Department of Chemistry, University of Dhaka, Dhaka-1000
  • Md Yousuf A Mollah Department of Chemistry, University of Dhaka, Dhaka-1000
  • M Muhibur Rahman University Grants Commission of Bangladesh, Agargaon, Dhaka-1207,
  • md Abu Bin Hasan susan Department of Chemistry, University of Dhaka, Dhaka-1000
Keywords: Preparation, Nanoparticles

Abstract

Nanoparticles of silver and copper have been synthesized by reduction of aqueous silver  nitrate and copper chloride solutions with sodium borohydride in anionic water-in-oil  (w/o) microemulsions, sodium dodecyl sulphate (SDS)/1-pentanol/cyclohexane/water.  Scanning electron microscopic (SEM) images, energy dispersive spectra (EDX) and UVspectra  have been used to characterize the resultant nanoparticles. The average size of the  nanoparticles has been found to be influenced by the water to surfactant molar ratio (Wo)  in the microemulsions. Smaller particles are obtained at low Wo, while higher Wo yields  larger particles. The antibiotic sensitivity of silver and copper nanoparticles against  Escherichia coli (E. coli) was tested by zone inhibition method using nanoparticles in  ethanol suspension. Both silver and copper nanoparticles showed the potential for use as  antibacterial agents against E. coli with sensitivity as good as conventional antibiotics.  Silver nanoparticles show higher antibacterial activity against E. coli, compared to copper nanoparticles. As the amount of the nanoparticles in the suspension decreases, antibacterial activity decreases; however the concentration dependence on antibacterial  activity has been less pronounced.

DOI: http://dx.doi.org/10.3329/jbcs.v25i1.11777

Journal of Bangladesh Chemical Society, Vol. 25(1), 71-79, 2012

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Abstract
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Published
2012-09-03
How to Cite
Hossain, S., Fatema, U. K., Mollah, M., Rahman, M., & Hasan susan, md. (2012). Microemulsions as Nanoreactors for Preparation of Nanoparticles with Antibacterial Activity. Journal of the Bangladesh Chemical Society, 25(1), 71-79. https://doi.org/10.3329/jbcs.v25i1.11777
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Articles