Prevalence and Antibiotic Sensitivity Pattern of Enterococci Causing Urinary Tract Infection in a Tertiary Care Hospital of Bangladesh

Authors

  • Suman Khisa Lt Col , MBBS, DCP, MCPS, FCPS, Associate Professor of Microbiology, Armed Forces Medical College, Dhaka
  • Arif Ahmed Khan Brig Gen (Retd), MBBS, MCPS, FCPS, Vice President, Bangladesh Society of Medical Microbiology
  • Jamal Pasha Chowdhury Col, MBBS, DCP, MCPS, FCPS, Classified Specialist in Pathology, CMH Savar
  • Wasila Rahman Lt Col, MBBS, DCP, MCPS, FCPS, Classified Specialist in Pathology, CMH Saidpur.

DOI:

https://doi.org/10.3329/jafmc.v20i2.80407

Keywords:

Enterococci, UTI, antibiotic sensitivity patterns

Abstract

Background: Enterococcus has emerged as one of the important causative agents of urinary tract infection (UTI) in recent years. Their resistance to many antimicrobials has increased in last few decades.

Objective: To find out the appropriate antibiotics to treat the patient caused by different species of enterococci.

Methods: This cross-sectional observational study was carried out in Armed Forces Institute of Pathology (AFIP) and Combined Military Hospital (CMH), Dhaka Cantonment, Dhaka during the period of December 2022 to May 2023. During this period, a total of 118 enterococci were isolated from urine specimen as a causative agent of UTI.

Results: 6130 urine specimens were cultured. 1056 specimens yielded growth of significant bacteria. 118 isolates were confirmed as enterococci (isolation rate11.17%). The mean age was 25.9±8.5 years and female to male ratio was 1.8:1. Maximum resistance was seen against azithromycin (84.7%), followed by tetracycline (72.1%), doxycycline (61.86%), ciprofloxacin (55.1%) and carbapenems (45%). Most sensitive antibiotic was linezolid (resistance rate 0%), followed by vancomycin (resistance rate 4.23%), combination of amoxicillin and clavulanic acid (resistance rate 13.5%), nitrofurantoin (17.8%).

Conclusion: According to this study, linezolid was the most effective antibiotic followed by vancomycin, combination of amoxicillin-clavulanic acid and nitrofurantoin. In this study, sensitivity to nitrofurantoin and amoxicillin-clavulanic was quite promising (77.2% and 86.5% respectively). So these two drugs may be included as a first line treatment regime to treat enterococcal UTI.

JAFMC Bangladesh, Vol 20, No 2 (December) 2024: 27-29

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Published

2025-07-01

How to Cite

Khisa, S., Khan, A. A., Chowdhury, J. P., & Rahman, W. (2025). Prevalence and Antibiotic Sensitivity Pattern of Enterococci Causing Urinary Tract Infection in a Tertiary Care Hospital of Bangladesh. Journal of Armed Forces Medical College, Bangladesh, 20(2), 27–29. https://doi.org/10.3329/jafmc.v20i2.80407

Issue

Vol. 20 No. 2 (2024)

Section

Original Papers

License

Submission of a manuscript for publication implies the transfer of the copyright from the author to the publisher upon acceptance. Accepted manuscripts become the permanent property of the Journal of Armed Forces Medical College and may not be reproduced by any means in whole or in part without the written consent of the publisher.