Efficacy of Low Dose Low Molecular Weight Heparin in the Treatment of Cutaneous Lichen Planus

  • MSI Khan Graded Spl in Dermatologyand Venereology, AFMI, Dhaka Cantt.
  • MN Uddin Commandant, AFMC, Dhaka Cantt.
  • MOR Shah Former Classified Specialist in Dermatology and Venereology, CMH, Dhaka Cantt
  • L Khondker Prof of Dermatology and Venereology, BSMMU, Dhaka
  • MS Hasan Asst Prof of Dermatology and Venereology, AFMC, Dhaka Cantt.
Keywords: Cutaneous lichen planus, efficacy of low molecular weight heparin

Abstract

Introduction: Lichen planus is a common pruritic, inflammatory disease of the skin, mucous membranes, nail and hair follicles. Low dose low molecular weight heparin is administered in the treatment of cutaneous lichen planus.

Objective: The objective is to evaluate the efficacy of low dose low molecular weight heparin in the treatment of cutaneous lichen planus.

Materials and Methods: An interventional study was carried out in the department of Dermatology and Venereology, Combined Military Hospital (CMH), Dhaka. Total thirty seven patients of cutaneous lichen planus were selected by purposive type non-probability sampling technique. Data were collected by face to face interview and clinical examination.

Results: It was observed that before treatment, the score of cutaneous lichen planus lesion was 6.83 ± 1.30 and after treatment was 3.83 ± 1.18 and t test was found statistically significant (P<0.05). Improvement was shown in 26 (70.27%) cases. Out of these, response was good in 23 (88.46%), fair in 2 (7.69%) and poor in 1 (3.85%) cases.

Conclusion: The study revealed that low dose low molecular weight heparin has remarkable efficacy profile as treatment option for cutaneous lichen planus.

DOI: http://dx.doi.org/10.3329/jafmc.v9i1.18717

Journal of Armed Forces Medical College Bangladesh Vol.9(1) 2013: 2-7

Downloads

Download data is not yet available.
Abstract
554
PDF
457
Published
2014-04-28
How to Cite
Khan, M., Uddin, M., Shah, M., Khondker, L., & Hasan, M. (2014). Efficacy of Low Dose Low Molecular Weight Heparin in the Treatment of Cutaneous Lichen Planus. Journal of Armed Forces Medical College, Bangladesh, 9(1), 2-7. https://doi.org/10.3329/jafmc.v9i1.18717
Section
Original Papers