Comparison of the GRACE and TIMI Risk Scores in Predicting the Angiographic Severity of Coronary Artery Disease in Patients with non STelevation Myocardial Infarction

Authors

  • Sharadindu Shekhar Roy Department of Cardiology, National Institute of Cardiovascular Diseases, Dhaka
  • STM Abu Azam Department of Cardiology, National Institute of Cardiovascular Diseases, Dhaka
  • Md Khalequzzaman Department of Cardiology, National Institute of Cardiovascular Diseases, Dhaka
  • Mohammad Ullah Department of Cardiology, National Institute of Cardiovascular Diseases, Dhaka
  • Samir Kumar Kundu Department of Cardiology, National Institute of Cardiovascular Diseases, Dhaka
  • Muhammad Azmol Hossain Department of Cardiology, National Institute of Cardiovascular Diseases, Dhaka
  • ABM Riaz Kawsar Department of Cardiology, National Institute of Cardiovascular Diseases, Dhaka
  • Anup Kumar Howlader Department of Cardiology, National Institute of Cardiovascular Diseases, Dhaka
  • Mohammad Khalilur Rahman Siddiqui Department of Cardiology, National Institute of Cardiovascular Diseases, Dhaka
  • Abul Hasnat Md Jafar Department of Cardiology, National Institute of Cardiovascular Diseases, Dhaka

DOI:

https://doi.org/10.3329/cardio.v10i1.34361

Keywords:

Myocardial infarction, Coronary artery disease, TIMI risk score, GRACE risk score

Abstract

Background: The superiority of the GRACE and TIMI risk scores in predicting the angiographic severity of coronary artery disease in patients with non ST-elevation myocardial infarction (NSTEMI) has not yet been established. This study was done to compare the GRACE and TIMI risk scores in predicting the angiographic severity of coronary artery disease in this group of patients.

Method: The cross sectional study done in the Department of Cardiology, NICVD, Dhaka. The patients admitted with NSTEMI were evaluated to calculate the GRACE and TIMI risk score from April, 2015 to April, 2016.Coronary angiogram was done during index hospitalization and the severity of the coronary artery disease was assessed by vessel score and Gensini score.

Results: Of 115 patients assessed, a positive correlation of the vessel score and Gensini score was observed with both the GRACE and TIMI risk scores (p=<0.001) and the GRACE score (r=0.59) correlated better than the TIMI score (r=0.52). The GRACE score presented area under the Receiver Operating Characteristic (ROC) curve of 0.844(95% CI = 0.774 0.914) significantly superior to the area under the ROC curve of 0.752(95% CI =0.658 0.846) of the TIMI score for the difference between the two scores.

Conclusion: Both the GRACE and TIMI scores had good predictive value in predicting the severity of coronary artery disease in the patients with NSTEMI but when both the scores were compared, the GRACE score was found to be superior and correlated better with the severity of coronary artery disease.

Cardiovasc. j. 2017; 10(1): 45-51

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Published

2017-10-22

How to Cite

Roy, S. S., Azam, S. A., Khalequzzaman, M., Ullah, M., Kundu, S. K., Hossain, M. A., Kawsar, A. R., Howlader, A. K., Siddiqui, M. K. R., & Md Jafar, A. H. (2017). Comparison of the GRACE and TIMI Risk Scores in Predicting the Angiographic Severity of Coronary Artery Disease in Patients with non STelevation Myocardial Infarction. Cardiovascular Journal, 10(1), 45–51. https://doi.org/10.3329/cardio.v10i1.34361

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Original Articles