Association of Glycosylated Haemoglobin Level with the Severity of Coronary Artery Disease in NSTEMI Diabetic Patients

Authors

  • Mahmod Mohammad Salim Deaprtment of Cardiology, Bashundhara Ad-din Medical College Hospital, Dhaka
  • Malik Fazila Tun Nesa Department of Cardiology, NHF& RI
  • Rahman Mohammad Arif Department of Cardiology ,NICVD, Dhaka
  • Hossain Mohammad Delwar Upazilla Health Complex, Sarail, Dhaka
  • Mandal Md Raihan Masum Department of Cardiology, TMMC.

DOI:

https://doi.org/10.3329/cardio.v8i1.24767

Keywords:

HbA1C, Coronary Artery Disease

Abstract

Background: Relation between diabetes mellitus and ischemic heart disease is well established. But the effect of HbA1C on severity of coronary artery disease remains uncertain in non-ST elevation myocardial infarction and diabetic patient. Objective of our study was to know the relationship of HbA1C with the severity of coronary artery disease.

Methods: In this cross sectional analytical study a total of 104 NSTEMI diabetic patients were enrolled by purposive sampling. They were divided into two groups according to the level of HbA1C, Group-I patients having HbA1C<7% and Group-II patients having HbA1C >7%. Vessel score and Gensini score was calculated from coronary angiogram and compared between groups.

Results: Single vessel disease were significantly higher in group-I compared to Group-II( 38.5% vs 7.7% in Group-I vs Group-II,p<0.05). Double vessel disease were higher in group-II compared to Group-I but the difference was statistically not significant (42.3% vs 48.1% in Group-I vs Group-II respectively (p>0.05). Triple vessel disease were significantly higher in group-II compared to Group- I (19.2% vs 44.4% in Group-I vs Group-II,p<0.05). Mean Vessel score was higher in Group-II compared to Group-I(1.73 ± 0.86 vs 2.50 ±0.70 in Group-I vs Group-II, p<0.05). Mean Gensini score was higher in Group-II compared to Group-I (44.6 ± 38.4 vs 76.9 ± 44.6 in Group-I vs Group-II, p<0.05). There were significant positive linear correlation between HbA1C and Vessels score and Gensini score (p<0.05).

Conclusion: This study may be concluded that the presence of HbA1C >7% are associated with of severe coronary artery disease in NSTEMI with diabetes mellitus.

Cardiovasc. j. 2015; 8(1): 43-48

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Published

2015-08-28

How to Cite

Salim, M. M., Nesa, M. F. T., Arif, R. M., Delwar, H. M., & Masum, M. M. R. (2015). Association of Glycosylated Haemoglobin Level with the Severity of Coronary Artery Disease in NSTEMI Diabetic Patients. Cardiovascular Journal, 8(1), 43–48. https://doi.org/10.3329/cardio.v8i1.24767

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Section

Original Articles