Voltammetric study of the interaction of Cu(II) with proton pump inhibitor at different pH

  • R Biswas Department of chemistry, University of Dhaka, Dhaka 1000
  • MC Das Department of chemistry, University of Dhaka, Dhaka 1000
  • S Islam Department of chemistry, University of Dhaka, Dhaka 1000
  • MA Haque Department of chemistry, University of Dhaka, Dhaka 1000
  • AA Shaikh Department of chemistry, University of Dhaka, Dhaka 1000
Keywords: Transition metal ions, Proton pump inhibitors, Cyclic voltammetry, Glassy carbon electrode, Acetate buffer

Abstract

The electrochemical redox behavior of transition metal ion, Cu(II) at different pH in acetate buffer solution has been investigated using cyclic voltammetric method at glassy carbon electrode (GCE). Cyclic voltammograms of Cu(II) show two cathodic and an anodic peaks those remain identical at various pH. The cyclic voltammetric response of the metal ion has been observed in presence of proton pump inhibitors (PPIs) such as omeprazole, pantoprazole, esomeprazole and rabeprazole at various proportions of metal ion and PPIs. The nature of cyclic voltammograms of Cu(II) has been changed dramatically in presence of the PPIs due to the strong interaction between metal ion and PPIs. Almost similar interaction was noticed for all the PPIs. However, the maximum interaction was found at 1:2 molar ratio of Cu(II) and PPIs. The result could provide deep insight into the interaction between various metal ions and the PPIs that have been taken quite regularly in human body

Bangladesh J. Sci. Ind. Res. 50(3), 219-226, 2015

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Author Biography

R Biswas, Department of chemistry, University of Dhaka, Dhaka 1000


Published
2015-11-05
How to Cite
Biswas, R., Das, M., Islam, S., Haque, M., & Shaikh, A. (2015). Voltammetric study of the interaction of Cu(II) with proton pump inhibitor at different pH. Bangladesh Journal of Scientific and Industrial Research, 50(3), 219-226. https://doi.org/10.3329/bjsir.v50i3.25589
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Articles